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学科主题: 临床医学
题名:
Adequacy of peritoneal dialysis: Kt/V revisited
作者: Wang, L.1; Wang, T.2
关键词: Kt/V ; Dialysis index (DI) ; Solute removal index (SRI) ; Peritoneal dialysis
刊名: European Review for Medical and Pharmacological Sciences
发表日期: 2015-04-01
卷: 19, 期:7, 页:1272-1275
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy
关键词[WOS]: CAPD PATIENTS ; NUTRITION
英文摘要:

OBJECTIVE: Kt/V urea has been used to assess adequacy of peritoneal dialysis. However, Kt/V urea only reflects the clearance of solute without taking into consideration the effects of dietary protein intake (DPI). The objective of this study is to evaluate the value of Kt/V based on nitrogen balance and to observe if it is the best adequacy index.

METHODS: On the premise that nitrogen balance is obtained, we calculated the minimal adequate dialysate volume and dialysis index (DI), Kt/V and solute removal index (SRI). We compared the values of DI, Kt/V and SRI to evaluate the adequacy of peritoneal dialysis.

RESULTS: Kt/V was changed with DPI and body weight of continuous ambulatory peritoneal dialysis (CAPD) patients. We cannot define adequate dialysis with a single value while DPI and body weight are different since CAPD, SRI and Kt/V are numerically equal. However, dialysis index (DI) can reflect the minimal adequate dialysate volume when DPI and body weight are different and, thus, reflects the adequacy of dialysis.

CONCLUSIONS: DI reflects the balance between DPI and solute clearance; thus, it is more useful to evaluate dialysis adequacy than Kt/V and SRI in clinically stable peritoneal dialysis patients.

语种: 英语
项目资助者: Changjiang Scholars Program of Ministry of Education of the People&prime ; s Republic of China ; Ministry of Education
WOS记录号: WOS:000353587000024
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50765
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.Jiangsu Xuzhou First Peoples Hosp, Dept Internal Med, Xuzhou, Peoples R China
2.Peking Univ, Hosp 3, Dept Internal Med, Beijing 100871, Peoples R China

Recommended Citation:
Wang, L.,Wang, T.. Adequacy of peritoneal dialysis: Kt/V revisited[J]. European Review for Medical and Pharmacological Sciences,2015,19(7):1272-1275.
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