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学科主题临床医学
The GIANT study, a cluster-randomised controlled trial of efficacy of education of doctors about type 2 diabetes mellitus management guidelines in primary care practice
Reutens, Anne T.1; Hutchinson, Richard2; Ta Van Binh3; Cockram, Clive4; Deerochanawong, Chaicharn5; Ho, Low-Tone6; Ji, Linong7; Khalid, Bin Abdul Kadir8; Kong, Alice Pik Shan4; Lim-Abrahan, Mary Ann9; Tan, Chee-Eng10; Tjokroprawiro, Askandar11; Yoon, Kun-Ho12; Zimmet, Paul Z.1; Shaw, Jonathan E.1
关键词Type 2 Diabetes Glycaemic Control Practice Guidelines Primary Care Asia-pacific
刊名DIABETES RESEARCH AND CLINICAL PRACTICE
2012-10-01
DOI10.1016/j.diabres.2012.06.002
98期:1页:38-45
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Endocrinology & Metabolism
资助者GlaxoSmithKline Pte Ltd. ; GlaxoSmithKline Pte Ltd.
研究领域[WOS]Endocrinology & Metabolism
关键词[WOS]CLINICAL INERTIA ; ADHERENCE
英文摘要

Objectives: Primary aim: does general practitioner (GP) education on type 2 diabetes treatment improve HbA1c? Secondary aim: cardiovascular risk factors, hypoglycaemia, treatment intensification, health service utilisation, treatment barriers.

Methods: 99 Asia-Pacific GPs were cluster-randomised to be educated on regional diabetes management guidelines (intervention) or continue standard care (control). The intervention employed meetings, reminders, medical record summary sheets and patient result cards. Each GP recruited four type 2 diabetic patients, assessed at baseline, 6 and 12 months. The primary outcome was mean change in HbA1c from 0 to 6 months in patients with baseline HbA1c >= 6.5%.

Results: 361 patients (93%) completed 6 month follow-up. The primary HbA1c outcome was 0.11% (95% CI 0.27, 0.05) with intervention and 0.22% (95% CI 0.39, 0.05) in the control group (p = 0.340). The groups did not differ in control of other glycaemic indices, blood pressure or lipids after 6 or 12 months. In those with HbA1c >= 9.0%, approximately 50% received intensified treatment by 6 months, and 30% in the final 6 months. GPs identified treatment costs and patient reluctance to use insulin as management barriers.

Conclusions/interpretation: A structured GP education programme did not improve HbA1c in patients with type 2 diabetes. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

语种英语
资助者GlaxoSmithKline Pte Ltd. ; GlaxoSmithKline Pte Ltd.
WOS记录号WOS:000311026100010
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50830
专题北京大学第二临床医学院
作者单位1.Covance Pty Ltd, N Ryde, NSW, Australia
2.Natl Inst Diabet & Metab Disorders, Hanoi, Vietnam
3.Ransit Univ, Coll Med, Rajavithi Hosp, Bangkok, Thailand
4.Taipei Vet Gen Hosp, Taipei, Taiwan
5.Baker IDI Heart & Diabet Inst, Alfred Ctr, Melbourne, Vic 3004, Australia
6.Peking Univ, Peoples Hosp, Beijing 100871, Peoples R China
7.Monash Univ, Johor Baharu, Malaysia
8.Gleneagles Med Ctr, Singapore, Singapore
9.Airlangga Univ, Soetomo Teaching Hosp, Surabaya, Indonesia
10.Chinese Univ Hong Kong, Shatin, Hong Kong, Peoples R China
11.Univ Philippines, Coll Med, Manila, Philippines
12.Catholic Univ Korea, Kangnam St Marys Hosp, Seoul, South Korea
推荐引用方式
GB/T 7714
Reutens, Anne T.,Hutchinson, Richard,Ta Van Binh,et al. The GIANT study, a cluster-randomised controlled trial of efficacy of education of doctors about type 2 diabetes mellitus management guidelines in primary care practice[J]. DIABETES RESEARCH AND CLINICAL PRACTICE,2012,98(1):38-45.
APA Reutens, Anne T..,Hutchinson, Richard.,Ta Van Binh.,Cockram, Clive.,Deerochanawong, Chaicharn.,...&Shaw, Jonathan E..(2012).The GIANT study, a cluster-randomised controlled trial of efficacy of education of doctors about type 2 diabetes mellitus management guidelines in primary care practice.DIABETES RESEARCH AND CLINICAL PRACTICE,98(1),38-45.
MLA Reutens, Anne T.,et al."The GIANT study, a cluster-randomised controlled trial of efficacy of education of doctors about type 2 diabetes mellitus management guidelines in primary care practice".DIABETES RESEARCH AND CLINICAL PRACTICE 98.1(2012):38-45.
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