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学科主题: 口腔医学
题名:
Clinical evaluation of remineralization potential of casein phosphopeptide amorphous calcium phosphate nanocomplexes for enamel decalcification in orthodontics
作者: Wang Jun-xiang; Yan Yan; Wang Xiu-jing
关键词: casein phosphopeptide amorphous calcium phosphate ; enamel remineralization ; orthodontics
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2012-11-20
DOI: 10.3760/cma.j.issn.0366-6999.2012.22.020
卷: 125, 期:22, 页:4018-4021
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: FREE CHEWING GUM ; SUBSURFACE LESIONS ; IMAGE-ANALYSIS ; BOVINE ENAMEL ; IN-VITRO ; CPP-ACP ; DEMINERALIZATION ; FLUORIDE ; PREVENTION ; EROSION
英文摘要:

Background Enamel decalcification in orthodontics is a concern for dentists and methods to remineralize these lesions are the focus of intense research. The aim of this study was to evaluate the remineralizing effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) nanocomplexes on enamel decalcification in orthodontics.

Methods Twenty orthodontic patients with decalcified enamel lesions during fixed orthodontic therapy were recruited to this study as test group and twenty orthodontic patients with the similar condition as control group. GC Tooth Mousse, the main component of which is CPP-ACP, was used by each patient of test group every night after tooth-brushing for six months. For control group, each patient was asked to brush teeth with toothpaste containing 1100 parts per million (ppm) of fluoride twice a day. Standardized intraoral images were taken for all patients and the extent of enamel decalcification was evaluated before and after treatment over this study period. Measurements were statistically compared by t test.

Results After using CPP-ACP for six months, the enamel decalcification index (EDI) of all patients had decreased; the mean EDI before using CPP-ACP was 0.191 +/- 0.025 and that after using CPP-ACP was 0.183 +/- 0.023, the difference was significant (t=5.169, P <0.01). For control group, the mean EDI before treatment was 0.188 +/- 0.037 and that after treatment was 0.187 +/- 0.046, the difference was not significant (t=1.711, P >0.05).

Conclusion CPP-ACP can effectively improve the demineralized enamel lesions during orthodontic treatment, so it has some remineralization potential for enamel decalcification in orthodontics. Chin Med J 2012;125(22):4018-4021

语种: 英语
WOS记录号: WOS:000312748100021
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50843
Appears in Collections:北京大学口腔医学院_牙周科_期刊论文

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作者单位: Peking Univ, Sch Stomatol, Outpatient Dent Ctr, Dept Orthodont, Beijing 100034, Peoples R China

Recommended Citation:
Wang Jun-xiang,Yan Yan,Wang Xiu-jing. Clinical evaluation of remineralization potential of casein phosphopeptide amorphous calcium phosphate nanocomplexes for enamel decalcification in orthodontics[J]. CHINESE MEDICAL JOURNAL,2012,125(22):4018-4021.
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