IR@PKUHSC  > 北京大学基础医学院  > 心血管所
学科主题基础医学
Cardio: a web-based knowledge resource of genes and proteins related to cardiovascular disease
Zhang, QP; Lu, M; Shi, L; Rui, W; Zhu, XH; Chen, GH; Shang, T; Tang, J
关键词Specific Database Cardiovascular Disease Bioinformatics Cardiology
刊名INTERNATIONAL JOURNAL OF CARDIOLOGY
2004-11-01
DOI10.1016/j.ijcard.2003.09.008
97期:2页:245-249
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cardiac & Cardiovascular Systems
研究领域[WOS]Cardiovascular System & Cardiology
关键词[WOS]SEQUENCE DATABASE
英文摘要

Background: Cardiovascular disease (CVD) is the leading killer for human. In order to understand the linkage between cardiovascular diseases and genes or proteins.. it is essential to construct a database to organize the body of knowledge. While the existing molecular biological databases focus on the sequence and structural aspects of biological macromolecules, i.e. DNAs, RNAs and proteins, Cardio is the web-based system we built to provide a knowledge environment with visual interface to integrate information about major cardiovascular diseases in relation to genes and proteins. Methods: We collected the information from the web by using a group of software we developed and used a relational database management system to manage the information of these data. Results: Cardio consists of six sections: GENE, PROTEIN, DISEASE, DRUG, LINKS, and REFERENCE. Each section contains relevant information about the topic. Using a phenotype-driven approach, we can identify genetic mechanisms underlying the physiology and pathophysiology of specific cardiovascular disease, such as atherosclerosis, hypertension, heart failure, and stroke. Conclusion: The website titled "Database of Genes and Proteins Related to Cardiovascular Disease (Cardio)" is available at http://cardio.bjmu.edu.cn along with additional information on cardiovascular disease, supplementary materials and related figures. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000224547100013
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50896
Collection北京大学基础医学院_心血管所
作者单位Peking Univ, Inst Cardiovasc Sci, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Zhang, QP,Lu, M,Shi, L,et al. Cardio: a web-based knowledge resource of genes and proteins related to cardiovascular disease[J]. INTERNATIONAL JOURNAL OF CARDIOLOGY,2004,97(2):245-249.
APA Zhang, QP.,Lu, M.,Shi, L.,Rui, W.,Zhu, XH.,...&Tang, J.(2004).Cardio: a web-based knowledge resource of genes and proteins related to cardiovascular disease.INTERNATIONAL JOURNAL OF CARDIOLOGY,97(2),245-249.
MLA Zhang, QP,et al."Cardio: a web-based knowledge resource of genes and proteins related to cardiovascular disease".INTERNATIONAL JOURNAL OF CARDIOLOGY 97.2(2004):245-249.
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