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学科主题: 临床医学
题名:
Follow-up study of a pregnant woman 16 years after exposure in the Xinzhou radiation accident
作者: Zhang, Zhao-hui; Liang, Li; Zhang, Shu-lan; Jia, Ting-zhen; Liu, Qing-jie; Ma, Li-wen; Su, Xu; Liu, Ying; Chen, Sen; Qing, Bin; Cao, Bao-Shan; Xiao, Yu; Ying, Wen-chen; Zhang, Yu; Wang, Wen-xue; Wang, Zuo-yuan
刊名: JOURNAL OF RADIOLOGICAL PROTECTION
发表日期: 2011-12-01
DOI: 10.1088/0952-4746/31/4/N01
卷: 31, 期:4, 页:489-494
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Environmental Sciences ; Public, Environmental & Occupational Health ; Nuclear Science & Technology ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Nuclear Science & Technology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: CHERNOBYL ACCIDENT ; ATOMIC-BOMB
英文摘要:

To investigate the late effects of radiation on child-bearing women, a follow-up study was performed on a 39-year-old survivor 16 years after a (60)Co radiation accident. The woman, Fang, was 19 weeks pregnant at the time of exposure. Physical examinations, a full range of clinical laboratory and imaging tests, as well as cytogenetic analyses were conducted to evaluate Fang′s current health conditions. Fang shows the appearance of premature ageing and has a decreased menstrual period. Laboratory studies and imaging tests suggest nodular goitre disease and osteoporosis. Otherwise, no apparent abnormalities were found in the major organs. No malignant tumours were detected by either tumour markers or imaging tests. However, the existence of chromosome aberrations warrants long-term follow-up for tumour incidence in the future. Fang became pregnant 8 years after the accident, but suffered a miscarriage due to the death of the foetus at 6 months into the pregnancy. In conclusion, our findings suggest that the intrauterine death of the foetus might be associated with the previous exposure. There is no evidence of malignant tumours as of the date of the follow-up study. Non-cancerous diseases, i.e. thyroid disease and osteoporosis, which may be related to radiation exposure, are the major manifestations of the long-term effects of the accident.

语种: 英语
WOS记录号: WOS:000297254200010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50954
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Tumor Chemotherapy & Radiat Sickness, Beijing 100191, Peoples R China

Recommended Citation:
Zhang, Zhao-hui,Liang, Li,Zhang, Shu-lan,et al. Follow-up study of a pregnant woman 16 years after exposure in the Xinzhou radiation accident[J]. JOURNAL OF RADIOLOGICAL PROTECTION,2011,31(4):489-494.
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