IR@PKUHSC  > 北京大学第三临床医学院
学科主题临床医学
Follow-up study of a pregnant woman 16 years after exposure in the Xinzhou radiation accident
Zhang, Zhao-hui; Liang, Li; Zhang, Shu-lan; Jia, Ting-zhen; Liu, Qing-jie; Ma, Li-wen; Su, Xu; Liu, Ying; Chen, Sen; Qing, Bin; Cao, Bao-Shan; Xiao, Yu; Ying, Wen-chen; Zhang, Yu; Wang, Wen-xue; Wang, Zuo-yuan
刊名JOURNAL OF RADIOLOGICAL PROTECTION
2011-12-01
DOI10.1088/0952-4746/31/4/N01
31期:4页:489-494
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Environmental Sciences ; Public, Environmental & Occupational Health ; Nuclear Science & Technology ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Nuclear Science & Technology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]CHERNOBYL ACCIDENT ; ATOMIC-BOMB
英文摘要

To investigate the late effects of radiation on child-bearing women, a follow-up study was performed on a 39-year-old survivor 16 years after a (60)Co radiation accident. The woman, Fang, was 19 weeks pregnant at the time of exposure. Physical examinations, a full range of clinical laboratory and imaging tests, as well as cytogenetic analyses were conducted to evaluate Fang′s current health conditions. Fang shows the appearance of premature ageing and has a decreased menstrual period. Laboratory studies and imaging tests suggest nodular goitre disease and osteoporosis. Otherwise, no apparent abnormalities were found in the major organs. No malignant tumours were detected by either tumour markers or imaging tests. However, the existence of chromosome aberrations warrants long-term follow-up for tumour incidence in the future. Fang became pregnant 8 years after the accident, but suffered a miscarriage due to the death of the foetus at 6 months into the pregnancy. In conclusion, our findings suggest that the intrauterine death of the foetus might be associated with the previous exposure. There is no evidence of malignant tumours as of the date of the follow-up study. Non-cancerous diseases, i.e. thyroid disease and osteoporosis, which may be related to radiation exposure, are the major manifestations of the long-term effects of the accident.

语种英语
WOS记录号WOS:000297254200010
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50954
专题北京大学第三临床医学院
作者单位Peking Univ, Hosp 3, Dept Tumor Chemotherapy & Radiat Sickness, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Zhao-hui,Liang, Li,Zhang, Shu-lan,et al. Follow-up study of a pregnant woman 16 years after exposure in the Xinzhou radiation accident[J]. JOURNAL OF RADIOLOGICAL PROTECTION,2011,31(4):489-494.
APA Zhang, Zhao-hui.,Liang, Li.,Zhang, Shu-lan.,Jia, Ting-zhen.,Liu, Qing-jie.,...&Wang, Zuo-yuan.(2011).Follow-up study of a pregnant woman 16 years after exposure in the Xinzhou radiation accident.JOURNAL OF RADIOLOGICAL PROTECTION,31(4),489-494.
MLA Zhang, Zhao-hui,et al."Follow-up study of a pregnant woman 16 years after exposure in the Xinzhou radiation accident".JOURNAL OF RADIOLOGICAL PROTECTION 31.4(2011):489-494.
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