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学科主题: 药学
题名:
A Rapid Synthesis of 2-Aryl Polyhydroxylated Pyrrolidines
作者: Su, Jia-Kun1,2; Jia, Yue-Mei1; He, Ruirui3; Rui, Pei-Xin1; Han, Nanyin3; He, Xihui3; Xiang, Junfeng1; Chen, Xin3; Zhu, Jinghua3; Yu, Chu-Yi1
关键词: 2-aryl polyhydroxylated pyrrolidines ; iminosugars ; Bronsted acid ; polyhydroxylated cyclic nitrones ; Friedel-Crafts reaction
刊名: SYNLETT
发表日期: 2010-07-01
DOI: 10.1055/s-0029-1258085
期: 11, 页:1609-1616
收录类别: SCI ; IC ; CCR
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: STATE ANALOG INHIBITORS ; BETA-GALACTOSIDASE INHIBITORS ; N-RIBOSIDE HYDROLASES ; ALPHA-L-FUCOSIDASES ; CYCLIC NITRONES ; RADICAMINE-B ; STEREOSELECTIVE-SYNTHESIS ; NUCLEOPHILIC ADDITIONS ; INDOLE ALKALOIDS ; DIAZONIUM SALTS
英文摘要:

Friedel-Crafts-type reaction of electron-rich aromatic compounds with polyhydroxylated cyclic nitrones catalyzed by Bronsted acid afforded 2-aryl polyhydroxylated pyrrolidines in good to excellent yields with high diastereoselectivity under mild conditions.

语种: 英语
所属项目编号: 2009CB526511 ; 2009ZX09501-006 ; 20672117
项目资助者: National Basic Research Program of China ; Ministry of Science and Technology ; Ministry of Health of the P. R. of China ; Chinese Academy of Sciences ; National Natural Science Foundation of China
WOS记录号: WOS:000279048600004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50969
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, BNLMS, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

Recommended Citation:
Su, Jia-Kun,Jia, Yue-Mei,He, Ruirui,et al. A Rapid Synthesis of 2-Aryl Polyhydroxylated Pyrrolidines[J]. SYNLETT,2010(11):1609-1616.
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