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学科主题口腔医学
Improved bioactivity of PAN-based carbon nanofibers decorated with bioglass nanoparticles
Han, Bing1; Zhang, Xuehui2,4; Liu, Haiyang3,4; Deng, Xuliang2; Cai, Qing3; Jia, Xiaolong3; Yang, Xiaoping3; Wei, Yan2; Li, Gang3
关键词Carbon Nanofiber Bioglass Eletrospinning
刊名JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
2014-03-04
DOI10.1080/09205063.2013.861169
25期:4页:341-353
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Engineering, Biomedical ; Materials Science, Biomaterials ; Polymer Science
资助者National Basic Research Program of China ; Key Technologies R&amp ; D Program of China ; National High Technology Research and Development Program of China ; Beijing municipal Science &amp ; Technology Commission Projects ; Key International S&amp ; T Cooperation Projects ; Science Foundation of Peking University School and Hospital of Stomatology ; National Basic Research Program of China ; Key Technologies R&amp ; D Program of China ; National High Technology Research and Development Program of China ; Beijing municipal Science &amp ; Technology Commission Projects ; Key International S&amp ; T Cooperation Projects ; Science Foundation of Peking University School and Hospital of Stomatology
研究领域[WOS]Engineering ; Materials Science ; Polymer Science
关键词[WOS]IN-VITRO ; MECHANICAL-PROPERTIES ; TISSUE REGENERATION ; GLASS ; HYDROXYAPATITE ; MINERALIZATION ; KINETICS ; COATINGS
英文摘要

Composite nanofibers composed of polyacrylonitrile (PAN)-based carbon nanofibers and bioactive glass (BG) nanoparticles have been prepared by electrospinning and in situ sintering. Morphology observation showed that the BG nanoparticles of size 20-50nm were uniformly distributed on the surface of composite nanofibers with 350nm average diameter after carbonization. Biological mineralization indicated the formation of apatite-like layer on the surface of composite nanofibers, in which the composition of carbonate hydroxyapatite was proved by FTIR and XRD analysis. Cell growth dynamics according to cellular morphology, CCK-8 assay, and alkaline phosphatase activity assay exhibited better cell adhesion, proliferation, and osteogenic induction of bone marrow-derived mesenchymal stem cells cultured on the composite nanofibers, which suggested the higher bioactivity of composite nanofibers compared to pure PAN-based carbon nanofibers.

语种英语
所属项目编号2012CB933900 ; 2012BAI07B00 ; 2011AA030100 ; Z121100005212007 ; 2011DFA32190 ; YS020212
资助者National Basic Research Program of China ; Key Technologies R&amp ; D Program of China ; National High Technology Research and Development Program of China ; Beijing municipal Science &amp ; Technology Commission Projects ; Key International S&amp ; T Cooperation Projects ; Science Foundation of Peking University School and Hospital of Stomatology ; National Basic Research Program of China ; Key Technologies R&amp ; D Program of China ; National High Technology Research and Development Program of China ; Beijing municipal Science &amp ; Technology Commission Projects ; Key International S&amp ; T Cooperation Projects ; Science Foundation of Peking University School and Hospital of Stomatology
WOS记录号WOS:000329486600002
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50991
专题北京大学口腔医学院_牙周科
作者单位1.Peking Univ, Sch & Hosp Stomatol, Dept Orthodont, Beijing 100081, Peoples R China
2.Beijing Univ Chem Technol, Minist Educ, Key Lab Carbon Fiber & Funct Polymers, Beijing 100029, Peoples R China
3.Tsinghua Univ, Dept Mat Sci & Engn, State Key Lab New Ceram & Fine Proc, Beijing 100084, Peoples R China
4.Peking Univ, Sch & Hosp Stomatol, Dept Geriatr Dent, Beijing 100081, Peoples R China
推荐引用方式
GB/T 7714
Han, Bing,Zhang, Xuehui,Liu, Haiyang,et al. Improved bioactivity of PAN-based carbon nanofibers decorated with bioglass nanoparticles[J]. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,2014,25(4):341-353.
APA Han, Bing.,Zhang, Xuehui.,Liu, Haiyang.,Deng, Xuliang.,Cai, Qing.,...&Li, Gang.(2014).Improved bioactivity of PAN-based carbon nanofibers decorated with bioglass nanoparticles.JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,25(4),341-353.
MLA Han, Bing,et al."Improved bioactivity of PAN-based carbon nanofibers decorated with bioglass nanoparticles".JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION 25.4(2014):341-353.
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