北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 肾脏内科  > 期刊论文
学科主题: 临床医学
题名:
Identification of a gene associated with astragalus and angelica′s renal protective effects by silver staining mRNA differential display
作者: Yu, L; Lu, YY; Li, JZ; Wang, HY
关键词: kidney ; fibrosis ; gene expression ; astragalus ; angelica
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2002-06-01
卷: 115, 期:6, 页:923-927
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: MESSENGER-RNA ; KIDNEY
英文摘要:

Objective To identify genes associated with the chronic progression of renal disease and astragalus and angelica (A&A) ′ s renal protective effects.

Methods The technique of silver staining mRNA differential display (DD) was used to investigate changes of gene expression in normal, sclerotic and A&A treated sclerotic kidneys. We isolated genes differentially expressed during the progression of renal disease which could be normalized by A&A.

Results Several genes related to A&A′ s protective effects were isolated and one of them was confirmed by Northern blot.

Conclusion Silver staining mRNA differential display is a simple and effective technique for isolating differentially expressed genes. The isolated new gene may be related to the progression of chronic renal disease and contribute to A&A′s protective effects.

语种: 英语
WOS记录号: WOS:000176693300028
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51005
Appears in Collections:北京大学第一临床医学院_肾脏内科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Teaching Hosp 1, Dept Nephrol, Inst Nephrol, Beijing 100034, Peoples R China

Recommended Citation:
Yu, L,Lu, YY,Li, JZ,et al. Identification of a gene associated with astragalus and angelica′s renal protective effects by silver staining mRNA differential display[J]. CHINESE MEDICAL JOURNAL,2002,115(6):923-927.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yu, L]'s Articles
[Lu, YY]'s Articles
[Li, JZ]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yu, L]‘s Articles
[Lu, YY]‘s Articles
[Li, JZ]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace