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学科主题: 基础医学
题名:
Hepatitis E virus infection as a marker for contaminated community drinking water sources in Tibetan villages
作者: Toole, MJ1; Claridge, F1; Anderson, DA1; Zhuang, H1; Morgan, C1; Otto, B1; Stewart, T1
刊名: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
发表日期: 2006-02-01
卷: 74, 期:2, 页:250-254
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Public, Environmental & Occupational Health ; Tropical Medicine
研究领域[WOS]: Public, Environmental & Occupational Health ; Tropical Medicine
关键词[WOS]: CHINA
英文摘要:

In April-May 2001, a study was conducted to determine the prevalence of antibodies against hepatitis E virus (HEV) among 426 persons 8-49 years of age randomly selected from two groups of rural villages ill central Tibet. Group I villages were assessed in 1998 as having poor quality water sources; new water systems were then constructed prior to this Study. Group 2 villages had higher quality water and were not designated as priority villages for new systems prior to the study. No participants tested positive for IgM; only IgG was detected in the analyzed samples. Overall, 31% of the participants had ever been infected with HEV (95% confidence interval [CI] = 26.7-35.7%). The rate was higher in men (36.6%) than women (26.3%) and highest in those 30-39 years of age (49.1%). The rate of past infection was higher in group 1; the risk ratio was 2.77 (95% CI = 1.98-3.88). This difference is most likely the result of the poor quality of the original water sources in these villages. In resource-poor countries, HEV may be a useful health indicator reflecting the degree of contamination in village water sources. This may be especially important in rural areas (such as Tibet) where maternal mortality ratios are high because HEV may be an important cause of deaths during pregnancy in disease-endemic areas.

语种: 英语
WOS记录号: WOS:000235349600013
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51036
Appears in Collections:基础医学院_病原生物学系_期刊论文

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作者单位: 1.Burnet Inst Med Res & Publ Hlth, Melbourne, Vic 3001, Australia
2.Australian Red Cross Soc, Melbourne, Vic, Australia
3.Peking Univ, Hlth Sci Ctr, Dept Microbiol, Beijing 100871, Peoples R China

Recommended Citation:
Toole, MJ,Claridge, F,Anderson, DA,et al. Hepatitis E virus infection as a marker for contaminated community drinking water sources in Tibetan villages[J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE,2006,74(2):250-254.
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