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学科主题: 药学
题名:
Concise synthesis of novel acyclic analogues of cADPR with an ether chain as the northern moiety
作者: Wu, Huimin; Yang, Zhenjun; Zhang, Liangren; Zhang, Lihe
刊名: NEW JOURNAL OF CHEMISTRY
发表日期: 2010
DOI: 10.1039/b9nj00595a
卷: 34, 期:5, 页:956-966
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: CYCLIC-ADP-RIBOSE ; CALCIUM-RELEASE ACTIVITY ; CA2+-MOBILIZING AGENT ; CARBOCYCLIC-RIBOSE ; DERIVATIVES ; MIMICS ; DIPHOSPHORIBOSE ; SUBSTITUTION ; ANTAGONISTS ; HYDROLYSIS
英文摘要:

To study the properties of hydrolysates of cyclic adenosine diphosphate ribose (cADPR), a series of novel acyclic analogues of cADPR with an ether chain as the northern moiety and 8-substituted adenine or hypoxanthine as the base moiety were synthesized via an N(1) substitution construction, followed by bisphosphorylation, phosphoramidition or pyrophosphorylation. These compounds also provide various precursors for synthesizing cADPR analogues.

语种: 英语
所属项目编号: 90713005 ; 200800010078
项目资助者: National Natural Sciences Foundation of China ; Ministry of Education of China
WOS记录号: WOS:000277399200021
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51084
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

Recommended Citation:
Wu, Huimin,Yang, Zhenjun,Zhang, Liangren,et al. Concise synthesis of novel acyclic analogues of cADPR with an ether chain as the northern moiety[J]. NEW JOURNAL OF CHEMISTRY,2010,34(5):956-966.
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