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学科主题: 临床医学
题名:
Phenotypic and molecular identification of Sporothrix isolates of clinical origin in Northeast China
作者: Yu, Xiaohong1; Wan, Zhe2; Zhang, Zhenying1; Li, Fuqiu3; Li, Ruoyu2; Liu, Xiaoming1
关键词: Sporotrichosis ; Sporothrix globosa ; Calmodulin gene ; Northeast China
刊名: MYCOPATHOLOGIA
发表日期: 2013-08-01
DOI: 10.1007/s11046-013-9668-6
卷: 176, 期:1-2, 页:67-74
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Mycology
研究领域[WOS]: Mycology
关键词[WOS]: CUTANEOUS SPOROTRICHOSIS ; SCHENCKII ; PHYLOGENY
英文摘要:

Sporotrichosis is the most common deep mycosis in Northeast China which is an area of high epidemicity due to contact with reeds or cornstalks. In this study, we have characterized a total of 74 clinical isolates from fixed cutaneous, lymphocutaneous and disseminated clinical forms and from Heilongjiang, Jilin, and Liaoning provinces, respectively. All isolates (previously as Sporothrix schenckii) were identified as Sporothrix globosa according to their phenotypic characteristics and calmodulin gene sequences analysis. They were subdivided into two sub-clades (S. globosa I and S. globosa II). Most of our isolates (71/74) presented restricted growth at 37 A degrees C, which differed from a previous report. Up to now, S. globosa is the only pathogenic species in Northeast China, no matter what kind of clinical form and which region it is isolated from. Most of our clinical isolates (68/74) were clustered with three Chinese environmental isolates reported in the literature. The new findings of S. globosa isolates on division and thermotolerance at 37 A degrees C described in this study will help us gain a better understanding of S. globosa.

语种: 英语
WOS记录号: WOS:000322733800008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51094
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Dalian Med Univ, Affiliated Hosp 1, Dept Dermatol & Venerol, Dalian 116011, Peoples R China
2.Peking Univ, Hosp 1, Ctr Med Mycol & Mycoses, Dept Dermatol & Venerol, Beijing 100034, Peoples R China
3.Jilin Univ, Hosp 2, Dept Dermatol & Venerol, Changchun 130041, Peoples R China

Recommended Citation:
Yu, Xiaohong,Wan, Zhe,Zhang, Zhenying,et al. Phenotypic and molecular identification of Sporothrix isolates of clinical origin in Northeast China[J]. MYCOPATHOLOGIA,2013,176(1-2):67-74.
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