IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
Phenotypic and molecular identification of Sporothrix isolates of clinical origin in Northeast China
Yu, Xiaohong1; Wan, Zhe2; Zhang, Zhenying1; Li, Fuqiu3; Li, Ruoyu2; Liu, Xiaoming1
关键词Sporotrichosis Sporothrix Globosa Calmodulin Gene Northeast China
刊名MYCOPATHOLOGIA
2013-08-01
DOI10.1007/s11046-013-9668-6
176期:1-2页:67-74
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Mycology
研究领域[WOS]Mycology
关键词[WOS]CUTANEOUS SPOROTRICHOSIS ; SCHENCKII ; PHYLOGENY
英文摘要

Sporotrichosis is the most common deep mycosis in Northeast China which is an area of high epidemicity due to contact with reeds or cornstalks. In this study, we have characterized a total of 74 clinical isolates from fixed cutaneous, lymphocutaneous and disseminated clinical forms and from Heilongjiang, Jilin, and Liaoning provinces, respectively. All isolates (previously as Sporothrix schenckii) were identified as Sporothrix globosa according to their phenotypic characteristics and calmodulin gene sequences analysis. They were subdivided into two sub-clades (S. globosa I and S. globosa II). Most of our isolates (71/74) presented restricted growth at 37 A degrees C, which differed from a previous report. Up to now, S. globosa is the only pathogenic species in Northeast China, no matter what kind of clinical form and which region it is isolated from. Most of our clinical isolates (68/74) were clustered with three Chinese environmental isolates reported in the literature. The new findings of S. globosa isolates on division and thermotolerance at 37 A degrees C described in this study will help us gain a better understanding of S. globosa.

语种英语
WOS记录号WOS:000322733800008
Citation statistics
Cited Times:21[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51094
Collection北京大学第一临床医学院
作者单位1.Dalian Med Univ, Affiliated Hosp 1, Dept Dermatol & Venerol, Dalian 116011, Peoples R China
2.Peking Univ, Hosp 1, Ctr Med Mycol & Mycoses, Dept Dermatol & Venerol, Beijing 100034, Peoples R China
3.Jilin Univ, Hosp 2, Dept Dermatol & Venerol, Changchun 130041, Peoples R China
Recommended Citation
GB/T 7714
Yu, Xiaohong,Wan, Zhe,Zhang, Zhenying,et al. Phenotypic and molecular identification of Sporothrix isolates of clinical origin in Northeast China[J]. MYCOPATHOLOGIA,2013,176(1-2):67-74.
APA Yu, Xiaohong,Wan, Zhe,Zhang, Zhenying,Li, Fuqiu,Li, Ruoyu,&Liu, Xiaoming.(2013).Phenotypic and molecular identification of Sporothrix isolates of clinical origin in Northeast China.MYCOPATHOLOGIA,176(1-2),67-74.
MLA Yu, Xiaohong,et al."Phenotypic and molecular identification of Sporothrix isolates of clinical origin in Northeast China".MYCOPATHOLOGIA 176.1-2(2013):67-74.
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