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学科主题药学
New Efficient and Flexible Synthetic Route to Emivirine and Its Analogs
Li, Li1; Ma, Liying2; Wang, Xiaowei1; Liu, Junyi1,3
刊名JOURNAL OF HETEROCYCLIC CHEMISTRY
2013
DOI10.1002/jhet.987
50期:1页:164-168
收录类别SCI ; IC ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
资助者National Science Foundation of China ; Ministry of Science and Technology of China ; National Science Foundation of China ; Ministry of Science and Technology of China
研究领域[WOS]Chemistry
关键词[WOS]POTENT ; HEPT
英文摘要

A revised synthetic route to Emivirine (MKC-442) via properly substituted beta-keto ester converted from Meldrum′s Acid was developed. This method could be applied to the synthesis of a variety of MKC-442 analogues and open the way for their systematic biological evaluation.

语种英语
所属项目编号20672008 ; 20972011 ; 2005CB523103
资助者National Science Foundation of China ; Ministry of Science and Technology of China ; National Science Foundation of China ; Ministry of Science and Technology of China
WOS记录号WOS:000314187100027
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51140
专题北京大学药学院_化学生物学系
作者单位1.Peking Univ, Dept Biol Chem, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
2.Chinese Ctr Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Natl Ctr AIDS STD Control & Prevent NCAIDS, Beijing 100050, Peoples R China
3.Peking Univ, State Key Lab Nat & Biomimet Drug, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Li, Li,Ma, Liying,Wang, Xiaowei,et al. New Efficient and Flexible Synthetic Route to Emivirine and Its Analogs[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY,2013,50(1):164-168.
APA Li, Li,Ma, Liying,Wang, Xiaowei,&Liu, Junyi.(2013).New Efficient and Flexible Synthetic Route to Emivirine and Its Analogs.JOURNAL OF HETEROCYCLIC CHEMISTRY,50(1),164-168.
MLA Li, Li,et al."New Efficient and Flexible Synthetic Route to Emivirine and Its Analogs".JOURNAL OF HETEROCYCLIC CHEMISTRY 50.1(2013):164-168.
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