IR@PKUHSC  > 北京大学精神卫生研究所
学科主题精神卫生
Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions
Li, Hui-jie1; Wang, Peng-yun1,2; Jiang, Yang3; Chan, Raymond C. K.4; Wang, Hua-li5; Li, Juan1
关键词Mild Cognitive Impairment Neurological Soft Signs Neuropsychological Tests
刊名BEHAVIORAL AND BRAIN FUNCTIONS
2012-06-07
DOI10.1186/1744-9081-8-29
8
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Behavioral Sciences ; Neurosciences
研究领域[WOS]Behavioral Sciences ; Neurosciences & Neurology
关键词[WOS]INCIDENT ALZHEIMER-DISEASE ; NEUROCOGNITIVE FUNCTIONS ; PREFRONTAL CORTEX ; SCHIZOPHRENIA ; ABNORMALITIES ; INDIVIDUALS ; DYSFUNCTION ; INHIBITION ; INVENTORY ; DEFICITS
英文摘要

Background: Neurological abnormalities have been reported in people with amnestic mild cognitive impairment (aMCI). The current study aimed to examine the prevalence of neurological soft signs (NSS) in this clinical group and to examine the relationship of NSS to other neuropsychological performances.

Methods: Twenty-nine people with aMCI and 28 cognitively healthy elderly people were recruited for the present study. The NSS subscales (motor coordination, sensory integration, and disinhibition) of the Cambridge Neurological Inventory and a set of neuropsychological tests were administered to all the participants.

Results: People with aMCI exhibited significantly more motor coordination signs, disinhibition signs, and total NSS than normal controls. Correlation analysis showed that the motor coordination subscale score and total score of NSS were significantly inversely correlated with the combined Z-score of neuropsychological tests in aMCI group.

Conclusions: These preliminary findings suggested that people with aMCI demonstrated a higher prevalence of NSS compared to healthy elderly people. Moreover, NSS was found to be inversely correlated with the neuropsychological performances in persons with aMCI. When taken together, these findings suggested that NSS may play a potential important role and serve as a tool to assist in the early detection of aMCI.

语种英语
WOS记录号WOS:000311727100001
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51145
Collection北京大学精神卫生研究所
北京大学精神卫生研究所_精神科
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Ctr Aging Psychol, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100101, Peoples R China
3.Univ Kentucky, Coll Med, Dept Behav Sci, Lexington, KY 40536 USA
4.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
5.Peking Univ, Inst Mental Hlth, Dept Geriatr Psychiat, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Li, Hui-jie,Wang, Peng-yun,Jiang, Yang,et al. Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions[J]. BEHAVIORAL AND BRAIN FUNCTIONS,2012,8.
APA Li, Hui-jie,Wang, Peng-yun,Jiang, Yang,Chan, Raymond C. K.,Wang, Hua-li,&Li, Juan.(2012).Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions.BEHAVIORAL AND BRAIN FUNCTIONS,8.
MLA Li, Hui-jie,et al."Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions".BEHAVIORAL AND BRAIN FUNCTIONS 8(2012).
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
谷歌学术
谷歌学术Similar articles in
[Li, Hui-jie]'s Articles
[Wang, Peng-yun]'s Articles
[Jiang, Yang]'s Articles
百度学术
百度学术Similar articles in
[Li, Hui-jie]'s Articles
[Wang, Peng-yun]'s Articles
[Jiang, Yang]'s Articles
必应学术
必应学术Similar articles in
[Li, Hui-jie]'s Articles
[Wang, Peng-yun]'s Articles
[Jiang, Yang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.