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Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys
Kessler, R. C.1; Sampson, N. A.1; Berglund, P.2; Gruber, M. J.1; Al-Hamzawi, A.3; Andrade, L.4; Bunting, B.5; Demyttenaere, K.6; Florescu, S.7; de Girolamo, G.8; Gureje, O.9; He, Y.10; Hu, C.11,12; Huang, Y.13; Karam, E.14,15,16; Kovess-Masfety, V.17; Lee, S.18; Levinson, D.19; Medina Mora, M. E.20; Moskalewicz, J.21; Nakamura, Y.22; Navarro-Mateu, F.23; Browne, M. A. Oakley24; Piazza, M.25; Posada-Villa, J.26; Slade, T.27; ten Have, M.28; Torres, Y.29; Vilagut, G.30; Xavier, M.31,32; Zarkov, Z.33; Shahly, V.1; Wilcox, M. A.34
关键词Anxious Depression Comorbidity Epidemiology
刊名EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
2015-06-01
DOI10.1017/S2045796015000189
24期:3页:210-226
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Psychiatry
研究领域[WOS]Psychiatry
关键词[WOS]GENERALIZED ANXIETY DISORDER ; COGNITIVE-BEHAVIORAL THERAPY ; SUBSTANCE USE DISORDERS ; CO-MORBIDITY ; LONGITUDINAL COMMUNITY ; SERVICES UTILIZATION ; LIFETIME PREVALENCE ; PHYSICAL DISORDERS ; PANIC DISORDER ; PRIMARY-CARE
英文摘要

Background. To examine cross-national patterns and correlates of lifetime and 12-month comorbid DSM-IV anxiety disorders among people with lifetime and 12-month DSM-IV major depressive disorder (MDD).

Method. Nationally or regionally representative epidemiological interviews were administered to 74045 adults in 27 surveys across 24 countries in the WHO World Mental Health (WMH) Surveys. DSM-IV MDD, a wide range of comorbid DSM-IV anxiety disorders, and a number of correlates were assessed with the WHO Composite International Diagnostic Interview (CIDI).

Results. 45.7% of respondents with lifetime MDD (32.0-46.5% inter-quartile range (IQR) across surveys) had one of more lifetime anxiety disorders. A slightly higher proportion of respondents with 12-month MDD had lifetime anxiety disorders (51.7%, 37.8-54.0% IQR) and only slightly lower proportions of respondents with 12-month MDD had 12-month anxiety disorders (41.6%, 29.9-47.2% IQR). Two-thirds (68%) of respondents with lifetime comorbid anxiety disorders and MDD reported an earlier age-of-onset (AOO) of their first anxiety disorder than their MDD, while 13.5% reported an earlier AOO of MDD and the remaining 18.5% reported the same AOO of both disorders. Women and previously married people had consistently elevated rates of lifetime and 12-month MDD as well as comorbid anxiety disorders. Consistently higher proportions of respondents with 12-month anxious than non-anxious MDD reported severe role impairment (64.4 v. 46.0%; chi(2)(1)=187.0, p<0.001) and suicide ideation (19.5 v. 8.9%;chi(2)(1)=71.6, p<0.001). Significantly more respondents with 12-month anxious than non-anxious MDD received treatment for their depression in the 12 months before interview, but this difference was more pronounced in high-income countries (68.8 v. 45.4%; chi(2)(1)=108.8, p<0.001) than low/middle-income countries (30.3 v. 20.6%; chi(2)(1)=11.7, p<0.001).

Conclusions. Patterns and correlates of comorbid DSM-IV anxiety disorders among people with DSM-IV MDD are similar across WMH countries. The narrow IQR of the proportion of respondents with temporally prior AOO of anxiety disorders than comorbid MDD (69.6-74.7%) is especially noteworthy. However, the fact that these proportions are not higher among respondents with 12-month than lifetime comorbidity means that temporal priority between lifetime anxiety disorders and MDD is not related to MDD persistence among people with anxious MDD. This, in turn, raises complex questions about the relative importance of temporally primary anxiety disorders as risk markers v. causal risk factors for subsequent MDD onset and persistence, including the possibility that anxiety disorders might primarily be risk markers for MDD onset and causal risk factors for MDD persistence.

语种英语
WOS记录号WOS:000355273600006
引用统计
被引频次:34[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51198
专题北京大学精神卫生研究所
作者单位1.Netherlands Inst Mental Hlth & Addict, Utrecht, Netherlands
2.CES Univ, Ctr Excellence Res Mental Hlth, Medellin, Colombia
3.NCPHA, Dept Mental Hlth, Sofia, Bulgaria
4.Janssen Pharmaceut Res & Dev, Titusville, NJ USA
5.Al Qadisiya Univ, Coll Med, Diwania Governorate, Iraq
6.Univ Sao Paulo, Sch Med, Inst Psychiat, Sao Paulo, Brazil
7.Univ Ulster, Sch Psychol, Londonberry, Ireland
8.Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USA
9.Univ Michigan, Inst Social Res, Ann Arbor, MI USA
10.Katholieke Univ Leuven, Univ Hosp Gasthuisberg, Dept Psychiat, Leuven, Belgium
11.Natl Sch Publ Hlth Management & Profess Dev, Bucharest, Romania
12.IRCCS St John God Clin Res Ctr, Unit Epidemiol & Evaluat Psychiat, Brescia, Italy
13.Univ Ibadan, Dept Psychiat, Ctr Res & Training Mental Hlth Neurosci Drug & Al, Ibadan, Nigeria
14.Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Sch Med, Shanghai 200030, Peoples R China
15.Shenzhen Inst Mental Hlth, Shenzhen, Guangdong, Peoples R China
16.Shenzhen Kanging Hosp, Shenzhen, Guangdong, Peoples R China
17.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
18.Balamand Univ, Fac Med, Dept Psychiat & Clin Psychol, Beirut, Lebanon
19.St George Hosp Univ, Med Ctr, Dept Psychiat & Clin Psychol, Beirut, Lebanon
20.IDRAAC, Beirut, Lebanon
21.Paris Descartes Univ, EHESP, EA 4057, Paris, France
22.Chinese Univ Hong Kong, Dept Psychiat, Shatin, Hong Kong, Peoples R China
23.Minist Hlth Israel, Mental Hlth Serv, Jerusalem, Israel
24.Ramond e Fuente Muniz Natl Inst Psychiat, Mexico City, DF, Mexico
25.Inst Psychiat & Neurol, Warsaw, Poland
26.Jichi Med Univ, Dept Publ Hlth, Shimotsuke, Tochigi, Japan
27.CIBERESP Nodo, IMIB Arrixaca, Serv Murciano Salud, UDIF SM, Murcia, Spain
28.Natl Inst Hlth, Lima, Peru
29.Univ Colegio Mayor Cundinamarca, Bogota, Colombia
30.Univ Tasmania, Sch Med, Dept Psychiat, Hobart, Tas 7001, Australia
31.Univ New S Wales, Natl Drug & Alcohol Res Ctr, Sydney, NSW, Australia
32.IMIM Inst Hosp Mar Invest Med, Hlth Serv Res Unit, Edifici PRBB, Barcelona 08003, Spain
33.Univ Nova Lisboa, Dept Mental Hlth CEDOC, P-1200 Lisbon, Portugal
34.Univ Nova Lisboa, Fac Ciencias Med, P-1200 Lisbon, Portugal
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GB/T 7714
Kessler, R. C.,Sampson, N. A.,Berglund, P.,et al. Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys[J]. EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES,2015,24(3):210-226.
APA Kessler, R. C..,Sampson, N. A..,Berglund, P..,Gruber, M. J..,Al-Hamzawi, A..,...&Wilcox, M. A..(2015).Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys.EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES,24(3),210-226.
MLA Kessler, R. C.,et al."Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys".EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES 24.3(2015):210-226.
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