IR@PKUHSC  > 北京大学第二临床医学院  > 消化科
学科主题临床医学
Gastroesophageal Reflux Disease Questionnaire (GerdQ) in real-world practice: A national multicenter survey on 8065 patients
Bai, Yu1,2; Du, Yiqi1,2; Zou, Duowu1; Jin, Zhendong1; Zhan, Xianbao1; Li, Zhao-Shen1; Yang, Yunsheng5; Liu, Yulan6; Zhang, Shutian7; Qian, Jiaming9; Zhou, Liya10; Hao, Jianyu8; Chen, Dongfeng11; Fang, Dianchun12; Fan, Daiming14; Yu, Xiaofeng1; Sha, Weihong15; Nie, Yuqiang16; Zhang, Xiaofeng20; Xu, Hong22; Lv, Nonghua23; Jiang, Bo17; Zou, Xiaoping1; Fang, Jingyuan3; Fan, Jiangao4; Li, Yan1; Chen, Weichang25; Wang, Bangmao28; Zou, Yiyou24,29; Li, Youming21,26; Sun, Mingjun27; Chen, Qikui18; Chen, Minhu19; Zhao, Xiaoyan13; Chinese GerdQ Res Grp1
关键词Endoscopy: Upper Gi Epidemiology Esophagus Gastroenterology
刊名JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
2013-04-01
DOI10.1111/jgh.12125
28期:4页:626-631
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
资助者National Key Scientific and Technological Project ; AstraZeneca ; National Key Scientific and Technological Project ; AstraZeneca
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]PRIMARY-CARE ; ASIAN POPULATION ; CHINESE PATIENTS ; EPIDEMIOLOGY ; ESOPHAGITIS ; PREVALENCE ; MANAGEMENT ; DYSPEPSIA ; DIAGNOSIS ; CONSENSUS
英文摘要

Background and Aim Recently, Gastroesophageal Reflux Disease Questionnaire (GerdQ) has been developed for diagnosis of GERD. However, no study investigated its value in real-world practice. This study aimed to investigate whether GerdQ can be used for diagnosis of GERD in China. Methods A national multicenter survey was undertaken; all patients who underwent first diagnostic upper endoscopy for upper gastrointestinal (GI) symptoms were included. Data including the gender, age, symptoms, and endoscopic findings were prospectively recorded. The GerdQ score was measured before endoscopic procedure. Results Totally, 8065 patients were included. One thousand four hundred and thirty-five patients (17.8%) had reflux esophagitis. Among them, 620 (43.2%) patients′ GerdQ score was 8. For 2025 patients with GerdQ8, 620 (30.6%) were found to have reflux esophagitis, but the remaining 69.4% (1405/2025) were normal. Proportions of patients with reflux esophagitis increased in cut-off range from 318 for GerdQ. However, 22.2% of the patients with a GerdQ score2 also had reflux esophagitis. Twenty-eight (0.3%) patients were diagnosed to have upper GI malignancies, and 10 out of these 28 (35.7%) patients′ GerdQ score was 8. Conclusions The study suggests the proportions of Chinese patients with reflux esophagitis rise up with the increase of GerdQ score, and GerdQ may be used for diagnosis of GERD. However, low GerdQ score cannot exclude the possibility of reflux esophagitis. A minority of Chinese patients has high GerdQ score but is diagnosed with malignancies, even in the absence of alarm features.

语种英语
所属项目编号2012ZX09303011-002
资助者National Key Scientific and Technological Project ; AstraZeneca ; National Key Scientific and Technological Project ; AstraZeneca
WOS记录号WOS:000316817300007
Citation statistics
Cited Times:23[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51239
Collection北京大学第二临床医学院_消化科
作者单位1.Second Mil Med Univ, Changhai Hosp, Dept Gastroenterol, Shanghai 200433, Peoples R China
2.Fudan Univ, Huadong Hosp, Dept Gastroenterol, Shanghai 200433, Peoples R China
3.Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Dept Gastroenterol, Shanghai 200030, Peoples R China
4.Shanghai Jiao Tong Univ, Sch Med, Xinhua Hosp, Dept Gastroenterol, Shanghai 200030, Peoples R China
5.Peking Univ, Peoples Hosp, Dept Gastroenterol, Gen Hosp Peoples Liberat Army Hosp 301, Beijing 100871, Peoples R China
6.Peking Univ, Peoples Hosp, Dept Gastroenterol, Beijing 100871, Peoples R China
7.Capital Med Univ, Beijing Friendship Hosp, Dept Gastroenterol, Beijing, Peoples R China
8.Capital Med Univ, Beijing Chaoyang Hosp, Dept Gastroenterol, Beijing, Peoples R China
9.Peking Univ, Hosp 3, Dept Gastroenterol, Peking Union Med Coll Hosp, Beijing 100871, Peoples R China
10.Peking Univ, Hosp 3, Dept Gastroenterol, Beijing 100871, Peoples R China
11.Third Mil Med Univ, Daping Hosp, Dept Gastroenterol, Chongqing, Peoples R China
12.Third Mil Med Univ, Southwest Hosp, Dept Gastroenterol, Chongqing, Peoples R China
13.Third Mil Med Univ, Xinqiao Hosp, Dept Gastroenterol, Chongqing, Peoples R China
14.Fourth Mil Med Univ, Xijing Hosp Digest Dis, Dept Gastroenterol, Xian 710032, Shaanxi, Peoples R China
15.Southern Med Univ, Dept Gastroenterol, Guangdong Prov Peoples Hosp, Guangzhou, Guangdong, Peoples R China
16.Southern Med Univ, Dept Gastroenterol, Guangzhou Municipal Peoples Hosp 1, Affiliated Guangzhou Med Coll, Guangzhou, Guangdong, Peoples R China
17.Southern Med Univ, Nanfang Hosp, Dept Gastroenterol, Guangzhou, Guangdong, Peoples R China
18.Sun Yat Sen Univ, Affiliated Hosp 2, Dept Gastroenterol, Guangzhou 510275, Guangdong, Peoples R China
19.Sun Yat Sen Univ, Affiliated Hosp 1, Dept Gastroenterol, Guangzhou 510275, Guangdong, Peoples R China
20.Zhejiang Univ, Sch Med, Dept Gastroenterol, Peoples Hosp Hangzhou 1, Hangzhou 310003, Zhejiang, Peoples R China
21.Zhejiang Univ, Sch Med, Dept Gastroenterol, Affiliated Hosp 1, Hangzhou 310003, Zhejiang, Peoples R China
22.Jilin Univ, Hosp 1, Dept Gastroenterol, Changchun 130023, Jinlin, Peoples R China
23.Nanchang Univ, Affiliated Hosp 1, Dept Gastroenterol, Nanchang, Jiangxi, Peoples R China
24.Nanjing Univ, Sch Med, Affiliated Drum Tower Hosp, Dept Gastroenterol, Nanjing 210008, Jiangsu, Peoples R China
25.Suzhou Univ, Affiliated Hosp 1, Dept Gastroenterol, Suzhou, Jiangsu, Peoples R China
26.China Med Univ, Shengjing Hosp, Dept Gastroenterol, Shenyang, Liaoning, Peoples R China
27.China Med Univ, Dept Gastroenterol, Affiliated Hosp 1, Shenyang, Liaoning, Peoples R China
28.Tianjin Med Univ, Gen Hosp, Dept Gastroenterol, Tianjin, Peoples R China
29.Cent S Univ, Xiangya Hosp, Dept Gastroenterol, Changsha, Hunan, Peoples R China
Recommended Citation
GB/T 7714
Bai, Yu,Du, Yiqi,Zou, Duowu,et al. Gastroesophageal Reflux Disease Questionnaire (GerdQ) in real-world practice: A national multicenter survey on 8065 patients[J]. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY,2013,28(4):626-631.
APA Bai, Yu.,Du, Yiqi.,Zou, Duowu.,Jin, Zhendong.,Zhan, Xianbao.,...&Chinese GerdQ Res Grp.(2013).Gastroesophageal Reflux Disease Questionnaire (GerdQ) in real-world practice: A national multicenter survey on 8065 patients.JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY,28(4),626-631.
MLA Bai, Yu,et al."Gastroesophageal Reflux Disease Questionnaire (GerdQ) in real-world practice: A national multicenter survey on 8065 patients".JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 28.4(2013):626-631.
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