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学科主题: 临床医学
题名:
Childhood absence epilepsy: Elctroclinical features and diagnostic criteria
作者: Ma, Xiuwei1,2; Zhang, Yuehua1; Yang, Zhixian1; Liu, Xiaoyan1; Sun, Huihui1; Qin, Jiong1; Wu, Xiru1; Liang, Jianmin1,3
关键词: Childhood absence epilepsy ; Electroencephalogram ; Diagnosis
刊名: BRAIN & DEVELOPMENT
发表日期: 2011-02-01
DOI: 10.1016/j.braindev.2010.02.004
卷: 33, 期:2, 页:114-119
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: IDIOPATHIC GENERALIZED EPILEPSIES ; SEIZURES ; CLASSIFICATION ; CHILDREN
英文摘要:

Objective: To analyze the electroclinical features of children with childhood absence epilepsy (CAE) and discuss the diagnostic criteria for CAE. Methods: The video-electroencephalogram (VEEG) database in our hospital was searched using "absence seizures" and "3-Hz generalized spike and waves (GSW)" as key-words. Other epileptic syndromes with typical absence seizures were carefully excluded. Children meeting the CAE diagnostic criteria of the International League Against Epilepsy (ILAE) in 1989 were further evaluated with the diagnostic criteria proposed by Panayiotopoulos in 2005. Results: Totally 37 children met the 1989 ILAE criteria of CAE. The onset age of absence seizures ranged from 3 to 11 years. All patients had frequent absence seizures (5-60 times per day). Two patients (5.4%) had generalized tonic-clonic seizures. Hyperventilation induced absences in all patients. VEEG confirmed that 7 patients (18.9%) had only simple absences, 25 patients (67.6%) had only complex absences, and 5 patients (13.5%) had both simple and complex absences. Ictal EEG showed 3 Hz GSW discharges in all patients. The seizure duration ranged from 3 to 40 s. Four patients (10.8%) had two spikes per wave in ictal EEG. GSW fragments were found in 29 patients (78.4%) during sleep. Interictal polyspikes and waves were present in 17 patients (45.9%). Focal discharges predominantly in the anterior regions, were found in 22 patients (56.8%). Only 7 patients (18.9%) met the diagnostic criteria proposed by Panayiotopoulos in 2005. Conclusions: Few patients meeting the 1989 ILAE diagnostic criteria for CAE meet the new diagnostic criteria proposed by Panayiotopoulos in 2005. The new criteria for CAE are too strict to appropriately classify some patients. (C) 2010 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

语种: 英语
项目资助者: Research Foundation of Peking University First Hospital
WOS记录号: WOS:000287539900003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51260
Appears in Collections:北京大学第一临床医学院_儿科_期刊论文

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作者单位: 1.Peking Univ, Hosp 1, Dept Pediat, Beijing 100034, Peoples R China
2.Gen Hosp Beijing Dist, Bayi Childrens Hosp, Pla 100710, Peoples R China
3.Jilin Univ, Hosp 1, Dept Pediat, Changchun 130021, Peoples R China

Recommended Citation:
Ma, Xiuwei,Zhang, Yuehua,Yang, Zhixian,et al. Childhood absence epilepsy: Elctroclinical features and diagnostic criteria[J]. BRAIN & DEVELOPMENT,2011,33(2):114-119.
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