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学科主题: 临床医学
题名:
Present status of serum lipid levels in Beijing professional populations and its trend of changes over 15 years - a collaborative study of seven research and clinical laboratories in Beijing
作者: Li, HZ1; Wang, S1; Dong, J1; Zhu, LH1; Li, YL1; Gao, DL1; Tian, YP1; Dong, L1; Yang, L1; Li, SK1
关键词: Beijing professional populations ; lipid level ; lipid abnormality ; coronary heart disease
刊名: CLINICA CHIMICA ACTA
发表日期: 2005-02-01
DOI: 10.1016/j.cccn.2004.09.027
卷: 352, 期:1-2, 页:199-207
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medical Laboratory Technology
研究领域[WOS]: Medical Laboratory Technology
关键词[WOS]: CHOLESTEROL ; DISEASE ; RISK
英文摘要:

Background: China′s economy has been growing rapidly since 1980, which may have affected blood lipid levels. We carried out a study on serum lipid levels and prevalence of lipid abnormalities in Beijing professional populations in 2001-2002 and assessed the changing trends of lipid levels by comparing the results with that of a similar study in 1984-1986.

Methods: The study population included 31,068 government employees, medical and educational workers and scientific research personnel (male/female 6:4). All participants had physical examination and blood chemistry tests. Lipid parameters analyzed included total cholesterol, low- and high-density lipoprotein (LDL and HDL) cholesterol and triglyceride.

Results: Total cholesterol, LDL cholesterol and triglyceride concentrations increased significantly as compared with the 1984-1986 study, but the variations of lipid levels with age and sex remained unchanged. Age-adjusted prevalence of dyslipidemia and its distribution in different sexes and age groups were statistically analyzed. Comparing the results with the data of the US in the 1990s, total cholesterol concentration was lower by 16 mg/dl in men and 18 mg/dl in women, whereas LDL cholesterol concentration was lower by 20 mg/dl in men and 15 mg/dl in women. HDL cholesterol was significantly higher than the US in both genders.

Conclusions: The mean levels of total cholesterol (LDL cholesterol) increased rapidly in the 1980s, stabilized and descended slightly in 1990s. Coronary lipid risk level in Beijing professional populations is significantly lower than in the US. (C) 2004 Elsevier B.V. All rights reserved.

语种: 英语
WOS记录号: WOS:000226658600019
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51272
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Beijing Univ, Hosp 1, Beijing 100871, Peoples R China
2.Beijing Inst Cardiopulm Vasc Dis, Beijing, Peoples R China
3.Beijing Tong Ren Hosp, Beijing, Peoples R China
4.Beijing Union Med Coll Hosp, Beijing Inst Geriatr, Lipid Res Lab, Beijing 100730, Peoples R China
5.Beijing Union Med Coll Hosp, Dept Clin Chem, Beijing 100730, Peoples R China

Recommended Citation:
Li, HZ,Wang, S,Dong, J,et al. Present status of serum lipid levels in Beijing professional populations and its trend of changes over 15 years - a collaborative study of seven research and clinical laboratories in Beijing[J]. CLINICA CHIMICA ACTA,2005,352(1-2):199-207.
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