IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
Present status of serum lipid levels in Beijing professional populations and its trend of changes over 15 years - a collaborative study of seven research and clinical laboratories in Beijing
Li, HZ1; Wang, S1; Dong, J1; Zhu, LH1; Li, YL1; Gao, DL1; Tian, YP1; Dong, L1; Yang, L1; Li, SK1
关键词Beijing Professional Populations Lipid Level Lipid Abnormality Coronary Heart Disease
刊名CLINICA CHIMICA ACTA
2005-02-01
DOI10.1016/j.cccn.2004.09.027
352期:1-2页:199-207
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medical Laboratory Technology
研究领域[WOS]Medical Laboratory Technology
关键词[WOS]CHOLESTEROL ; DISEASE ; RISK
英文摘要

Background: China′s economy has been growing rapidly since 1980, which may have affected blood lipid levels. We carried out a study on serum lipid levels and prevalence of lipid abnormalities in Beijing professional populations in 2001-2002 and assessed the changing trends of lipid levels by comparing the results with that of a similar study in 1984-1986.

Methods: The study population included 31,068 government employees, medical and educational workers and scientific research personnel (male/female 6:4). All participants had physical examination and blood chemistry tests. Lipid parameters analyzed included total cholesterol, low- and high-density lipoprotein (LDL and HDL) cholesterol and triglyceride.

Results: Total cholesterol, LDL cholesterol and triglyceride concentrations increased significantly as compared with the 1984-1986 study, but the variations of lipid levels with age and sex remained unchanged. Age-adjusted prevalence of dyslipidemia and its distribution in different sexes and age groups were statistically analyzed. Comparing the results with the data of the US in the 1990s, total cholesterol concentration was lower by 16 mg/dl in men and 18 mg/dl in women, whereas LDL cholesterol concentration was lower by 20 mg/dl in men and 15 mg/dl in women. HDL cholesterol was significantly higher than the US in both genders.

Conclusions: The mean levels of total cholesterol (LDL cholesterol) increased rapidly in the 1980s, stabilized and descended slightly in 1990s. Coronary lipid risk level in Beijing professional populations is significantly lower than in the US. (C) 2004 Elsevier B.V. All rights reserved.

语种英语
WOS记录号WOS:000226658600019
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51272
专题北京大学第一临床医学院
北京大学临床肿瘤学院_肿瘤放疗科
北京大学精神卫生研究所_护理部
作者单位1.Beijing Univ, Hosp 1, Beijing 100871, Peoples R China
2.Beijing Inst Cardiopulm Vasc Dis, Beijing, Peoples R China
3.Beijing Tong Ren Hosp, Beijing, Peoples R China
4.Beijing Union Med Coll Hosp, Beijing Inst Geriatr, Lipid Res Lab, Beijing 100730, Peoples R China
5.Beijing Union Med Coll Hosp, Dept Clin Chem, Beijing 100730, Peoples R China
推荐引用方式
GB/T 7714
Li, HZ,Wang, S,Dong, J,et al. Present status of serum lipid levels in Beijing professional populations and its trend of changes over 15 years - a collaborative study of seven research and clinical laboratories in Beijing[J]. CLINICA CHIMICA ACTA,2005,352(1-2):199-207.
APA Li, HZ.,Wang, S.,Dong, J.,Zhu, LH.,Li, YL.,...&Li, SK.(2005).Present status of serum lipid levels in Beijing professional populations and its trend of changes over 15 years - a collaborative study of seven research and clinical laboratories in Beijing.CLINICA CHIMICA ACTA,352(1-2),199-207.
MLA Li, HZ,et al."Present status of serum lipid levels in Beijing professional populations and its trend of changes over 15 years - a collaborative study of seven research and clinical laboratories in Beijing".CLINICA CHIMICA ACTA 352.1-2(2005):199-207.
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