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Two flavonoids from the leaves of Morus alba induce differentiation of the human promyelocytic leukemia (HL-60) cell line
Kim, SY1; Gao, JJ1; Kang, K1
关键词Mulberry Leaf Flavonoid Differentiation
刊名BIOLOGICAL & PHARMACEUTICAL BULLETIN
2000-04-01
23期:4页:451-455
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]SUSPENSION CULTURE ; HYDROGEN-PEROXIDE ; INTERFERON-GAMMA ; PHORBOL DIESTER ; U937 CELLS ; COMPONENTS ; EXPRESSION ; ACID
英文摘要

Two flavonoids, quercetin-3-O-beta-D-glucopyranoside (1) and quercetin-3,7-di-O-beta-D-glucopyranoside (2), were isolated from the leaves of Morus alba (Moraceae). These two flavonoids exerted a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) at the concentration of 2 x 10(-4) M. Compound 2 also induced differentiation of the HL-60 cell line to express CD 66b and CD 14 antigens, These flavonoids exhibited significant free radical scavenging effects on 1,1-diphenyl-2-pieryl-hydrazyl radical.

语种英语
WOS记录号WOS:000086315500016
引用统计
被引频次:27[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51275
专题北京大学药学院
作者单位1.Cheju Natl Univ, Sch Med, Cheju 690756, South Korea
2.Kyung Hee Univ, Grad Sch EW Med Sci, Seoul 130701, South Korea
3.Beijing Med Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Kim, SY,Gao, JJ,Kang, K. Two flavonoids from the leaves of Morus alba induce differentiation of the human promyelocytic leukemia (HL-60) cell line[J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN,2000,23(4):451-455.
APA Kim, SY,Gao, JJ,&Kang, K.(2000).Two flavonoids from the leaves of Morus alba induce differentiation of the human promyelocytic leukemia (HL-60) cell line.BIOLOGICAL & PHARMACEUTICAL BULLETIN,23(4),451-455.
MLA Kim, SY,et al."Two flavonoids from the leaves of Morus alba induce differentiation of the human promyelocytic leukemia (HL-60) cell line".BIOLOGICAL & PHARMACEUTICAL BULLETIN 23.4(2000):451-455.
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