IR@PKUHSC  > 北京大学第一临床医学院  > 放射治疗科
学科主题临床医学
A study on small-world brain functional networks altered by postherpetic neuralgia
Zhang, Yue1; Liu, Jing2; Li, Longchuan3,4; Du, Minyi5; Fang, Wenxue5; Wang, Dongxin5; Jiang, Xuexiang2; Hu, Xiaoping4; Zhang, Jue1; Wang, Xiaoying2; Fang, Jing1
关键词Small-world Brain Functional Networks Resting-state Fmri Chronic Pain Postherpetic Neuralgia
刊名MAGNETIC RESONANCE IMAGING
2014-05-01
DOI10.1016/j.mri.2013.12.016
32期:4页:359-365
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]AFFECTIVE DIMENSION ; CHRONIC PAIN ; PERCEPTION ; MODULATION ; MECHANISMS ; DYNAMICS
英文摘要

Understanding the effect of postherpetic neuralgia (PHN) pain on brain activity is important for clinical strategies. This is the first study, to our knowledge, to relate PHN pain to small-world properties of brain functional networks. Functional magnetic resonance imaging (fMRI) was used to construct functional brain networks of the subjects during the resting state. Sixteen patients with PHN pain and 16 (8 males, 8 females for both groups) age-matched controls were studied. The PHN patients exhibited decreased local efficiency along with non-significant changes of global efficiency in comparison with the healthy controls. Moreover, regional nodal efficiency was found to be significantly affected by PHN pain in the areas related to sense (postcentral gyrus, inferior parietal gyrus and thalamus), memory/affective processes (parahippocampal gyms) and emotional activities (putamen). Significant correlation (p <0.05) was also found between the nodal efficiency of putamen and pain intensity in PHN patients. Our results suggest that PHN modulates the local efficiency, and the small-world properties of brain networks may have potentials to objectively evaluate pain information in clinic. (C) 2014 Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000333868200008
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51314
专题北京大学第一临床医学院_放射治疗科
北京大学第一临床医学院_麻醉科
作者单位1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
2.Emory Univ, Sch Med, Marcus Autism Ctr, Atlanta, GA USA
3.Peking Univ, Hosp 1, Dept Radiol, Beijing 100871, Peoples R China
4.Emory Univ, Georgia Inst Technol, Biomed Imaging Technol Ctr, Dept Biomed Engn, Atlanta, GA USA
5.Peking Univ, Hosp 1, Dept Anesthesiol, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Yue,Liu, Jing,Li, Longchuan,et al. A study on small-world brain functional networks altered by postherpetic neuralgia[J]. MAGNETIC RESONANCE IMAGING,2014,32(4):359-365.
APA Zhang, Yue.,Liu, Jing.,Li, Longchuan.,Du, Minyi.,Fang, Wenxue.,...&Fang, Jing.(2014).A study on small-world brain functional networks altered by postherpetic neuralgia.MAGNETIC RESONANCE IMAGING,32(4),359-365.
MLA Zhang, Yue,et al."A study on small-world brain functional networks altered by postherpetic neuralgia".MAGNETIC RESONANCE IMAGING 32.4(2014):359-365.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhang, Yue]的文章
[Liu, Jing]的文章
[Li, Longchuan]的文章
百度学术
百度学术中相似的文章
[Zhang, Yue]的文章
[Liu, Jing]的文章
[Li, Longchuan]的文章
必应学术
必应学术中相似的文章
[Zhang, Yue]的文章
[Liu, Jing]的文章
[Li, Longchuan]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。