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学科主题药学
Microfluidic sterilization
Zhang, Rui1,2; Huang, Jie1; Xie, Fei1; Wang, Baojun1; Chu, Ming3; Wang, Yuedan3; Li, Haichao4; Wang, Wei1,5,6; Zhang, Haixia1,5,6; Wu, Wengang1,5,6; Li, Zhihong1,5,6
刊名BIOMICROFLUIDICS
2014-05-01
DOI10.1063/1.4882776
8期:3
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemical Research Methods ; Biophysics ; Nanoscience & Nanotechnology ; Physics, Fluids & Plasmas
资助者Major State Basic Research Development Program (973 Program) ; National Natural Science Foundation of China ; 985-III program (clinical applications) in Peking University ; Major State Basic Research Development Program (973 Program) ; National Natural Science Foundation of China ; 985-III program (clinical applications) in Peking University
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics ; Science & Technology - Other Topics ; Physics
关键词[WOS]TOTAL ANALYSIS SYSTEMS ; HIGH-PRESSURE ; CELL-CULTURE ; MICROREACTOR
英文摘要

Nowadays, microfluidics is attracting more and more attentions in the biological society and has provided powerful solutions for various applications. This paper reported a microfluidic strategy for aqueous sample sterilization. A well-designed small microchannel with a high hydrodynamic resistance was used to function as an in-chip pressure regulator. The pressure in the upstream microchannel was thereby elevated which made it possible to maintain a boiling-free high temperature environment for aqueous sample sterilization. A 120 degrees C temperature along with a pressure of 400 kPa was successfully achieved inside the chip to sterilize aqueous samples with E. coli and Staphylococcus aureus inside. This technique will find wide applications in portable cell culturing, microsurgery in wild fields, and other related micro total analysis systems. (C) 2014 AIP Publishing LLC.

语种英语
所属项目编号2011CB309502 ; 91023045 ; 91323304
资助者Major State Basic Research Development Program (973 Program) ; National Natural Science Foundation of China ; 985-III program (clinical applications) in Peking University ; Major State Basic Research Development Program (973 Program) ; National Natural Science Foundation of China ; 985-III program (clinical applications) in Peking University
WOS记录号WOS:000339004500019
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51353
专题北京大学药学院
作者单位1.Peking Univ, Inst Microelect, Beijing 100871, Peoples R China
2.Peking Univ, Sch Basic Med Sci, Beijing 100191, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
4.Peking Univ, Peking Univ First Hosp, Beijing 100034, Peoples R China
5.Natl Key Lab Sci & Technol Micro Nano Fabricat, Beijing 100871, Peoples R China
6.Innovat Ctr MicroNanoelect & Integrated Syst, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Rui,Huang, Jie,Xie, Fei,et al. Microfluidic sterilization[J]. BIOMICROFLUIDICS,2014,8(3).
APA Zhang, Rui.,Huang, Jie.,Xie, Fei.,Wang, Baojun.,Chu, Ming.,...&Li, Zhihong.(2014).Microfluidic sterilization.BIOMICROFLUIDICS,8(3).
MLA Zhang, Rui,et al."Microfluidic sterilization".BIOMICROFLUIDICS 8.3(2014).
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