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学科主题临床医学
Overview of lupus nephritis management guidelines and perspective from Asia
Mok, Chi Chiu1; Yap, Desmond Y. H.2; Navarra, Sandra V.3; Liu, Zhi-hong4; Zhao, Ming-hui5; Lu, Liangjing6; Takeuchi, Tsutomu7; Avihingsanon, Yingyos8; Yu, Xue-qing9; Lapid, Elizabeth A.3; Lugue-Lizardo, Lenrore R.3; Sumethkul, Vasant10; Shen, Nan6; Chen, Shun-le6; Chan, Tak Mao2; ALNN1
关键词Asia Lupus Nephritis
刊名INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
2013-12-01
DOI10.1111/1756-185X.12212
16期:6页:625-636
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Rheumatology
研究领域[WOS]Rheumatology
关键词[WOS]COATED MYCOPHENOLATE SODIUM ; RANDOMIZED CONTROLLED-TRIAL ; LONG-TERM ; INTRAVENOUS CYCLOPHOSPHAMIDE ; ORAL CYCLOPHOSPHAMIDE ; INDUCTION TREATMENT ; PULSE METHYLPREDNISOLONE ; ANGIOTENSIN INHIBITION ; MAINTENANCE THERAPY ; MOFETIL
英文摘要

Lupus nephritis (LN) is a common and important manifestation of systemic lupus erythematosus (SLE). Evidence suggests higher rates of lupus renal involvement in Asian populations, and maybe more severe nephritis, compared with other racial or ethnic groups. The management of LN has evolved considerably over the past three decades, based on observations from clinical studies that investigated different immunosuppressive agents including corticosteroids, cyclophosphamide, azathioprine, mycophenolic acid, calcineurin inhibitors and novel biologic therapies. This is accompanied by improvements in both the short-term treatment response rate and long-term renal function preservation. Treatment guidelines for LN have recently been issued by rheumatology and nephrology communities in U.S.A. and Europe. In view of the racial difference in disease manifestation and response to therapy, and the substantial disease burden in Asia, a panel of 15 nephrologists and rheumatologists from different Asian regions with extensive experience in lupus nephritis - the Steering Group for the Asian Lupus Nephritis Network (ALNN) - met and discussed the management of lupus nephritis in Asian patients. The group has also reviewed and deliberated on the recently published recommendations from other parts of the world. This manuscript summarizes the discussions by the group and presents consensus views on the clinical management and treatment of adult Asian patients with LN, taking into account both the available evidence and expert opinion in areas where evidence remains to be sought.

语种英语
WOS记录号WOS:000330979200004
资助机构Wai Hung Charitable Foundation ; Estate of the late Mr Chan Wing Hei ; Astellas Pharma Co ; Hong Kong Ltd ; Roche Hong Kong Ltd ; Endowment Fund established for the &prime ; Yu Chiu Kwong Professorship in Medicine&prime ; University of Hong Kong
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51361
专题北京大学第一临床医学院_肾脏内科
作者单位1.Mahidol Univ, Div Nephrol, Bangkok 10700, Thailand
2.Tuen Mun Hosp, Div Rheumatol, Dept Med & Geriatr, Hong Kong, Hong Kong, Peoples R China
3.Jinling Hosp, Res Inst Nephrol, Nanjing, Jiangsu, Peoples R China
4.Beijing Univ, Hosp 1, Div Renal, Beijing 100871, Peoples R China
5.Renji Hosp, Dept Rheumatol, Shanghai, Peoples R China
6.Keio Univ, Sch Med, Div Rheumatol, Tokyo, Japan
7.Univ Hong Kong, Div Nephrol, Dept Med, Hong Kong, Hong Kong, Peoples R China
8.Univ Santo Tomas, Div Rheumatol, St Lukes Med Ctr, Manila, Philippines
9.Chulalongkorn Univ, Div Renal, Dept Med, Bangkok, Thailand
10.Sun Yat Sen Univ, Hosp 1, Dept Nephrol, Guangzhou 510275, Guangdong, Peoples R China
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GB/T 7714
Mok, Chi Chiu,Yap, Desmond Y. H.,Navarra, Sandra V.,et al. Overview of lupus nephritis management guidelines and perspective from Asia[J]. INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES,2013,16(6):625-636.
APA Mok, Chi Chiu.,Yap, Desmond Y. H..,Navarra, Sandra V..,Liu, Zhi-hong.,Zhao, Ming-hui.,...&ALNN.(2013).Overview of lupus nephritis management guidelines and perspective from Asia.INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES,16(6),625-636.
MLA Mok, Chi Chiu,et al."Overview of lupus nephritis management guidelines and perspective from Asia".INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES 16.6(2013):625-636.
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