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IR@PKUHSC  > 北京大学第一临床医学院  > 肾脏内科  > 期刊论文
学科主题: 临床医学
题名:
Overview of lupus nephritis management guidelines and perspective from Asia
作者: Mok, Chi Chiu1; Yap, Desmond Y. H.2; Navarra, Sandra V.3; Liu, Zhi-hong4; Zhao, Ming-hui5; Lu, Liangjing6; Takeuchi, Tsutomu7; Avihingsanon, Yingyos8; Yu, Xue-qing9; Lapid, Elizabeth A.3; Lugue-Lizardo, Lenrore R.3; Sumethkul, Vasant10; Shen, Nan6; Chen, Shun-le6; Chan, Tak Mao2; ALNN1
关键词: Asia ; lupus ; nephritis
刊名: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
发表日期: 2013-12-01
DOI: 10.1111/1756-185X.12212
卷: 16, 期:6, 页:625-636
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Rheumatology
研究领域[WOS]: Rheumatology
关键词[WOS]: COATED MYCOPHENOLATE SODIUM ; RANDOMIZED CONTROLLED-TRIAL ; LONG-TERM ; INTRAVENOUS CYCLOPHOSPHAMIDE ; ORAL CYCLOPHOSPHAMIDE ; INDUCTION TREATMENT ; PULSE METHYLPREDNISOLONE ; ANGIOTENSIN INHIBITION ; MAINTENANCE THERAPY ; MOFETIL
英文摘要:

Lupus nephritis (LN) is a common and important manifestation of systemic lupus erythematosus (SLE). Evidence suggests higher rates of lupus renal involvement in Asian populations, and maybe more severe nephritis, compared with other racial or ethnic groups. The management of LN has evolved considerably over the past three decades, based on observations from clinical studies that investigated different immunosuppressive agents including corticosteroids, cyclophosphamide, azathioprine, mycophenolic acid, calcineurin inhibitors and novel biologic therapies. This is accompanied by improvements in both the short-term treatment response rate and long-term renal function preservation. Treatment guidelines for LN have recently been issued by rheumatology and nephrology communities in U.S.A. and Europe. In view of the racial difference in disease manifestation and response to therapy, and the substantial disease burden in Asia, a panel of 15 nephrologists and rheumatologists from different Asian regions with extensive experience in lupus nephritis - the Steering Group for the Asian Lupus Nephritis Network (ALNN) - met and discussed the management of lupus nephritis in Asian patients. The group has also reviewed and deliberated on the recently published recommendations from other parts of the world. This manuscript summarizes the discussions by the group and presents consensus views on the clinical management and treatment of adult Asian patients with LN, taking into account both the available evidence and expert opinion in areas where evidence remains to be sought.

语种: 英语
项目资助者: Wai Hung Charitable Foundation ; Estate of the late Mr Chan Wing Hei ; Astellas Pharma Co ; Hong Kong Ltd ; Roche Hong Kong Ltd ; Endowment Fund established for the &prime ; Yu Chiu Kwong Professorship in Medicine&prime ; University of Hong Kong
WOS记录号: WOS:000330979200004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51361
Appears in Collections:北京大学第一临床医学院_肾脏内科_期刊论文

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作者单位: 1.Mahidol Univ, Div Nephrol, Bangkok 10700, Thailand
2.Tuen Mun Hosp, Div Rheumatol, Dept Med & Geriatr, Hong Kong, Hong Kong, Peoples R China
3.Jinling Hosp, Res Inst Nephrol, Nanjing, Jiangsu, Peoples R China
4.Beijing Univ, Hosp 1, Div Renal, Beijing 100871, Peoples R China
5.Renji Hosp, Dept Rheumatol, Shanghai, Peoples R China
6.Keio Univ, Sch Med, Div Rheumatol, Tokyo, Japan
7.Univ Hong Kong, Div Nephrol, Dept Med, Hong Kong, Hong Kong, Peoples R China
8.Univ Santo Tomas, Div Rheumatol, St Lukes Med Ctr, Manila, Philippines
9.Chulalongkorn Univ, Div Renal, Dept Med, Bangkok, Thailand
10.Sun Yat Sen Univ, Hosp 1, Dept Nephrol, Guangzhou 510275, Guangdong, Peoples R China

Recommended Citation:
Mok, Chi Chiu,Yap, Desmond Y. H.,Navarra, Sandra V.,et al. Overview of lupus nephritis management guidelines and perspective from Asia[J]. INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES,2013,16(6):625-636.
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