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学科主题: 临床医学
题名:
Plasmacytoid urothelial carcinoma of the bladder
作者: Qin, Meihua1; Wang, Gangping2; Sun, Yanqing1; He, Qun3,4
关键词: CD138 ; E-cadherin ; plasmacytoid ; urothelial carcinoma
刊名: INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY
发表日期: 2014-04-01
DOI: 10.4103/0377-4929.134730
卷: 57, 期:2, 页:320-322
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pathology
研究领域[WOS]: Pathology
关键词[WOS]: URINARY-BLADDER ; VARIANT
英文摘要:

Plasmacytoid urothelial carcinoma (PUC) of the urinary bladder is an uncommon and aggressive variant of urothelial carcinoma associated with late presentation and poor prognosis. Immunohistochemical examination showing expression of epithelial markers, CD138, and losing the membranous expression of E-cadherin confirms evidence of PUC. Here, we report a case of bladder PUC of a 74-year-old male who presented with hematuria. A transurethral biopsy revealed urothelial carcinoma with plasmacytoid appearance. The diagnostic dilemmas of this unusual variant of urothelial malignancy and its clinical impact are discussed. The pathological diagnosis was PUC (High-grade, pT4N2M0) with diffuse muscle, small tracts, and vascular invasion, in which almost of the areas studied on the tissue section showed Plasmacytoid differentiation.

语种: 英语
WOS记录号: WOS:000338218200035
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51395
Appears in Collections:北京大学第一临床医学院_病理科_期刊论文

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作者单位: 1.Rizhao Peoples Hosp, Dept Urol, Rizhao 276826, Shandong, Peoples R China
2.Rizhao Peoples Hosp, Dept Pathol, Rizhao 276826, Shandong, Peoples R China
3.Peking Univ, Hosp 1, Dept Pathol, Beijing 100871, Peoples R China
4.Peking Univ, Inst Urol, Beijing 100871, Peoples R China

Recommended Citation:
Qin, Meihua,Wang, Gangping,Sun, Yanqing,et al. Plasmacytoid urothelial carcinoma of the bladder[J]. INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY,2014,57(2):320-322.
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