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Oligosaccharide synthesis and library assembly by one-pot sequential glycosylation strategy
Wang, YH; Zhang, LH; Ye, XS
关键词Carbohydrate One-pot Synthesis Glycosylation Oligosaccharide Library Review
刊名COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
2006
9期:1页:63-75
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemical Research Methods ; Chemistry, Applied ; Pharmacology & Pharmacy
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]HYPERACUTE REJECTION RESPONSE ; SOLID-PHASE SYNTHESIS ; BUILDING-BLOCKS ; TRISACCHARIDE LIBRARIES ; COMBINATORIAL SYNTHESIS ; PRACTICAL SYNTHESIS ; AMINO-ACIDS ; REACTIVITY ; GLYCOSIDES ; GLYCOPROTEINS
英文摘要

The oligosaccharide residue in glycoconjugates located in cell membranes is responsible for intercellular recognition and interaction: it acts as a receptor for proteins, hormones, and microorganisms and governs immune reactions. These significant activities have stimulated great interest in the field of oligosaccharides and glycoconjugates. Although many advances have been made in the synthesis of oligosaccharides, more convenient and efficient methods are still needed. This review describes one of these new methods-the one-pot sequential glycosylation approach as a potent tool for oligosaccharide assembly. The oligosaccharide library construction in a one-pot fashion is also summarized.

语种英语
WOS记录号WOS:000234791100010
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51407
专题北京大学药学院
作者单位Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
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GB/T 7714
Wang, YH,Zhang, LH,Ye, XS. Oligosaccharide synthesis and library assembly by one-pot sequential glycosylation strategy[J]. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING,2006,9(1):63-75.
APA Wang, YH,Zhang, LH,&Ye, XS.(2006).Oligosaccharide synthesis and library assembly by one-pot sequential glycosylation strategy.COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING,9(1),63-75.
MLA Wang, YH,et al."Oligosaccharide synthesis and library assembly by one-pot sequential glycosylation strategy".COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 9.1(2006):63-75.
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