IR@PKUHSC  > 北京大学深圳医院
学科主题临床医学
Comparison of Mastoscopic and Conventional Axillary Lymph Node Dissection in Breast Cancer: Long-term Results From a Randomized, Multicenter Trial
Luo, Chengyu1; Guo, Wenbin2; Yang, Jie3; Sun, Qiuru4; Wei, Wei5; Wu, Suhua6; Fang, Shubing7; Zeng, Qingliang1; Zhao, Zhensheng8; Meng, Fanjie9; Huang, Xuandong10; Zhang, Xianlan11; Li, Ruihua12; Ma, Xiufeng1; Luo, Chaoying13; Yang, Yun14
刊名MAYO CLINIC PROCEEDINGS
2012-12-01
DOI10.1016/j.mayocp.2012.07.022
87期:12页:1153-1161
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
资助者Capital Medical Development Fund ; Capital Medical Development Fund
研究领域[WOS]General & Internal Medicine
关键词[WOS]SENTINEL-NODE ; NEOADJUVANT CHEMOTHERAPY ; INITIAL-EXPERIENCE ; PRIOR LIPOSUCTION ; CLINICAL-TRIAL ; TUMOR-CELLS ; LYMPHADENECTOMY ; SURGERY ; BIOPSY ; MASTECTOMY
英文摘要

Objective: To compare the long-term results of mastoscopic axillary lymph node dissection (MALND) and conventional axillary lymph node dissection (CALND).

Patients and Methods: From January 1, 2003, through December 31, 2005, a group of 1027 consecutive patients with operable breast cancer were randomly assigned to 1 of 2 study groups: MALND and CALND. The median follow-up was 63 months. The primary end points of the study were operative outcomes, complication reduction, function conservation, and cosmetics. The secondary end points were disease-free and overall survival.

Results: The mean operative blood loss in the MALND group was less than in the CALND group (P<.001). The patients who underwent MALND had less axillary pain, numbness or paresthesias, and arm swelling (P<.001). The aesthetic appearance of the axilla in the MALND group was much better than that in the CALND group (P=.001 at 6 months and P=.002 at 24 months). A significant difference was found between the 2 groups in distant metastasis (P=.04). The disease-free survival rate was 64.5% in the MALND group and 60.8% in the CALND group (P=.88). The overall survival rate was 81.7% in the MALND group and 78.6% in the CALND group (P=.95).

Conclusion: Compared with CALND, MALND has advantages in operative outcomes, complication reduction, function conservation, and cosmetics. c 2012 Mayo Foundation for Medical Education and Research square Mayo Clin Proc. 2012;87(12):1153-1161

语种英语
资助者Capital Medical Development Fund ; Capital Medical Development Fund
WOS记录号WOS:000312806000010
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51527
Collection北京大学深圳医院
作者单位1.Heibei Concord Hosp, Hebei, Peoples R China
2.Yanjing Univ, Affiliated Hosp, Coll Med, Beijing, Peoples R China
3.N China Oil Gen Hosp, Hebei, Peoples R China
4.Huaian Hosp, Huaian, Jiangsu, Peoples R China
5.Guilin Med Coll, Affiliated Hosp, Guangxi, Peoples R China
6.Guangdong Med Univ, Shunde Hosp, Guangzhou, Guangdong, Peoples R China
7.Xinjiang Kelamayi Cent Hosp, Xinjiang, Peoples R China
8.Dalian Med Univ, Da Lian Hosp, Liaoning, Peoples R China
9.Capital Med Univ, Fuxing Hosp, Beijing 100038, Peoples R China
10.Zhongshan Univ, Fo Shan Hosp, Zhongshan, Guangdong, Peoples R China
11.Qingdao Univ, Wei Hai Hosp, Coll Med, Qingdao, Shandong, Peoples R China
12.Beijing Univ, Shenzhen Hosp, Beijing 100871, Guangdong, Peoples R China
13.Anhui Med Coll, Affiliated Hosp, Hefei, Anhui, Peoples R China
14.Capital Med Univ, Dept Epidemiol & Hlth Stat, Beijing 100038, Peoples R China
Recommended Citation
GB/T 7714
Luo, Chengyu,Guo, Wenbin,Yang, Jie,et al. Comparison of Mastoscopic and Conventional Axillary Lymph Node Dissection in Breast Cancer: Long-term Results From a Randomized, Multicenter Trial[J]. MAYO CLINIC PROCEEDINGS,2012,87(12):1153-1161.
APA Luo, Chengyu.,Guo, Wenbin.,Yang, Jie.,Sun, Qiuru.,Wei, Wei.,...&Yang, Yun.(2012).Comparison of Mastoscopic and Conventional Axillary Lymph Node Dissection in Breast Cancer: Long-term Results From a Randomized, Multicenter Trial.MAYO CLINIC PROCEEDINGS,87(12),1153-1161.
MLA Luo, Chengyu,et al."Comparison of Mastoscopic and Conventional Axillary Lymph Node Dissection in Breast Cancer: Long-term Results From a Randomized, Multicenter Trial".MAYO CLINIC PROCEEDINGS 87.12(2012):1153-1161.
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