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Fluvoxamine in the treatment of depression: results from a Chinese population
Gu, NF1; Cai, ZJ1; Liang, S1; Zhou, TX1; Xu, JM1; Zhang, XB1; Wu, WY1; Ming, L1
关键词Depression Fluvoxamine Selective Serotonin Reuptake Inhibitor China
刊名PRIMARY CARE PSYCHIATRY
2004
DOI10.1185/135525704X10746
9期:3页:89-94
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal ; Psychiatry
研究领域[WOS]General & Internal Medicine ; Psychiatry
关键词[WOS]SEROTONIN TRANSPORTER GENE ; MAJOR DEPRESSION ; DOUBLE-BLIND ; MEDICAL OUTCOMES ; PAROXETINE ; OUTPATIENTS ; MANAGEMENT ; FLUOXETINE ; DISORDERS ; COMMUNITY
英文摘要

This multicentre, open, post-marketing study was conducted to investigate the efficacy and tolerability of fluvoxamine in patients with depressive disorders in China. A total of 120 Chinese patients were treated with fluvoxamine (50 mg/day for one week followed by 100-150 mg/day) for 6 weeks. The majority of patients (76.7%) were stabilised on a dose of 100 mg/day for the duration of the study. There was a significant clinical response to fluvoxamine; more than 85% of patients were considered responders at the end of the study as assessed by their improvement on the Hamilton Depression Rating Scale (greater than or equal to50% reduction in score). These findings were confirmed by the Clinical Global Impression (CGI) - Severity scale, CGI Improvement scale and CGI - Quality of life scale. Fluvoxamine was well tolerated; the most common adverse events were dry mouth, nausea and vomiting, and constipation. In conclusion, fluvoxamine at a dose of 100-150 mg/day is effective, safe and well-tolerated in the treatment of people with depression.

语种英语
WOS记录号WOS:000225872500004
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51568
专题北京大学精神卫生研究所
作者单位1.Suzhou Guangji Hosp, Suzhou, Peoples R China
2.Peking Univ, Inst Mental Hlth, Beijing, Peoples R China
3.Hongkou Dist Mental Hlth Ctr, Shanghai, Peoples R China
4.Nanjing Brain Hosp, Nanjing, Peoples R China
5.Shanghai Mental Hlth Ctr, Dept Psychiat, Shanghai 200030, Peoples R China
6.Capital Med Univ, Beijing Andling Hosp, Beijing, Peoples R China
7.Fudan Univ, Shanghai Zongshan Hosp, Shanghai 200433, Peoples R China
8.Tongji Univ, Shanghai Tongji Hosp, Mental & Somatol Dept, Shanghai 200092, Peoples R China
推荐引用方式
GB/T 7714
Gu, NF,Cai, ZJ,Liang, S,et al. Fluvoxamine in the treatment of depression: results from a Chinese population[J]. PRIMARY CARE PSYCHIATRY,2004,9(3):89-94.
APA Gu, NF.,Cai, ZJ.,Liang, S.,Zhou, TX.,Xu, JM.,...&Ming, L.(2004).Fluvoxamine in the treatment of depression: results from a Chinese population.PRIMARY CARE PSYCHIATRY,9(3),89-94.
MLA Gu, NF,et al."Fluvoxamine in the treatment of depression: results from a Chinese population".PRIMARY CARE PSYCHIATRY 9.3(2004):89-94.
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