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学科主题: 临床医学
题名:
Ultrafiltration capacity and peritoneal fluid kinetics in continuous ambulatory peritoneal dialysis patients
作者: Zhe, Xing-wei; Tian, Xin-kui; Cheng, Lei; Wang, Tao
关键词: peritoneal dialysis ; fluid kinetics ; ultrafiltration capacity
刊名: ARTIFICIAL ORGANS
发表日期: 2008
DOI: 10.1111/j.1525-1594.2007.00453.x
卷: 32, 期:1, 页:61-65
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Engineering, Biomedical ; Transplantation
研究领域[WOS]: Engineering ; Transplantation
关键词[WOS]: TRANSPORT TEST ; ADEQUACY ; CAVITY ; TIME ; CAPD
英文摘要:

Volume control is critical for peritoneal dialysis. Although peritoneal equilibration test (PET) has been used to clarify the peritoneal membrane characteristics, it is not able to adequately predict peritoneal fluid removal and optimize appropriately the dwell time. In the present study, we applied computer simulation and performed a more detailed evaluation of the fluid kinetics in patients with different ultrafiltration (UF) capacity. Patients who used three to four exchanges of 2.27% glucose dialysate per day (poor UF capacity group), and patients who used three to four exchanges of 1.36% glucose dialysate per day (good UF capacity group) to achieve adequate amount of peritoneal fluid removal were included in the present analysis. All included patients were asked to record appropriately their dialysis exchanges for the assessment of their peritoneal fluid transport characteristics. Seventeen continuous ambulatory peritoneal dialysis patients were selected in the present study, nine in poor UF capacity group and eight in good UF capacity group. Patients in poor UF capacity group had significantly higher daily glucose exposure, higher dialysate-to-plasma ratio of creatinine (D/P creatinine) values, and higher peritoneal fluid absorption rate, K-e, as compared to patients with good UF capacity. Our results suggest that patients with poor UF capacity have significant higher peritoneal small solute transport rate, and more importantly, higher peritoneal fluid absorption rate as compared to patients with good UF capacity.

语种: 英语
WOS记录号: WOS:000251859500009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51682
Appears in Collections:北京大学第三临床医学院_肾内科_期刊论文

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作者单位: Peking Univ, Hosp 3, Div Nephrol, Beijing 100083, Peoples R China

Recommended Citation:
Zhe, Xing-wei,Tian, Xin-kui,Cheng, Lei,et al. Ultrafiltration capacity and peritoneal fluid kinetics in continuous ambulatory peritoneal dialysis patients[J]. ARTIFICIAL ORGANS,2008,32(1):61-65.
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