北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学药学院  > 期刊论文
学科主题: 药学
题名:
Flavanoids from the stems of Aquilaria sinensis
作者: Chen Dong; Bi Dan; Song Yue-Lin; Tu Peng-Fei
关键词: Aquilaria sinensis ; Chemical constituents ; Flavonoids ; NO
刊名: CHINESE JOURNAL OF NATURAL MEDICINES
发表日期: 2012-07-01
DOI: 10.3724/SP.J.1009.2012.00287
卷: 10, 期:4, 页:287-291
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Integrative & Complementary Medicine ; Pharmacology & Pharmacy
研究领域[WOS]: Integrative & Complementary Medicine ; Pharmacology & Pharmacy
关键词[WOS]: NITRIC-OXIDE
英文摘要:

AIM: To study the chemical constituents from the stems of Aquilaria sinensis (Lour.) Gilg. METHODS: Chromatographic separations of silica gel, Sephadex LH-20 and prep-HPLC were used. All the structures were elucidated on the basis of chemical and spectroscopic analysis. RESULTS: Twelve flavonoids were isolated and their structures were identified as aquilarinoside AI (1), lethedioside A (2), 7, 4′-dimethylapigenin-5-O-xylosylglucoside (3), lethedoside A (4), 7-hydroxyl-4′-methyl-5-O- glucosideflavonoid (5), 7, 3′-dimethyl-4′-hydroxyl-5-O-glucosideflavonoide (6), 7, 4′-dimethyl-5-O-glucosideflavonoide (7), 5-hydroxyl-7, 4′-dimethoxyflavone (8), luteolin-7, 3′, 4′-trimethyl (9), hydroxylgenkwanin (10), 5, 7-dihydroxyl-4′-methoxyflavone (11), and formononetin (12). CONCLUSION: Compound 1 is a new flavone glycoside, and compounds 2, 4-7 were isolated from genus Aquilaria sinensis for the first time. 5-O-glycosylflavones 1-7 showed inhibitory activity for nitric oxide (NO) production by activated RAW 264.7 cells.

语种: 英语
所属项目编号: 2009ZX311-004 ; 2009ZX0308-004
项目资助者: Ministry of Science and Technology, China
WOS记录号: WOS:000306300200010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51726
Appears in Collections:北京大学药学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Sch Pharmaceut Sci, Hlth Sci Ctr, State Key Lab Nat & Biomimet Drugs, Beijing 100101, Peoples R China

Recommended Citation:
Chen Dong,Bi Dan,Song Yue-Lin,et al. Flavanoids from the stems of Aquilaria sinensis[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2012,10(4):287-291.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Chen Dong]'s Articles
[Bi Dan]'s Articles
[Song Yue-Lin]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Chen Dong]‘s Articles
[Bi Dan]‘s Articles
[Song Yue-Lin]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace