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Spatiotemporal-resolved nanoparticle synthesis via simple programmed microfluidic processes
Shen, Xiaomiao1; Song, Yujun2; Li, Shuai1; Li, Runsheng1; Ji, Shaoxia1; Li, Qing1; Duan, Huiping1; Xu, Riwei3; Yang, Wantai3; Zhao, Kai4; Rong, Rong4; Wang, Xiaoying4
刊名RSC ADVANCES
2014
DOI10.1039/c4ra04168b
4期:64页:34179-34188
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]CORE-SHELL NANOPARTICLES ; MAGNETIC-PROPERTIES ; NANOCRYSTAL SYNTHESIS ; COBALT NANOPARTICLES ; OXIDE NANOPARTICLES ; GOLD NANOCRYSTALS ; SCALE SYNTHESIS ; INTERFACE ; REACTOR ; GROWTH
英文摘要

The spatiotemporally splitting nanoparticle (NP) formation route is critical but extremely challenging in terms of methodology development for large-scale continuous production of NPs with defined sizes, structures and properties, particularly for magnetic and/or hybrid NPs. Herein, we present transparent, chip-based, simple programmed microfluidic processes (C-SPMPs) and sequentially developed, transparent micro-tubing based simple programmed microfluidic processes (MT-SPMPs). By C-SPMPs and MT-SPMPs, four stages including mixing/reaction, nucleation, growth and termination during NPs formation could be well-separated and observed by the changes of flow color along the microchannels for the first time using magnetic Co, Fe, Ni, CoFe and NiFe NPs as examples. A four-section mechanism was proposed and discussed for the development of these strategies by the in situ monitoring of the changes in the relative C=O and C-O bond content in the coordinating cyclic lactam groups in the bi-channel solvent (i.e., N-methy-2-pyrrolidone) and the stabilizer (i.e., polyvinylpyrrolidone) and UV-vis spectra of reaction solution using the formation of CoFe NPs as a model. These strategies are beneficial for optimizing each stage by tuning channel length, flow rate, reactant concentration, and reaction and termination temperatures for the synthesis of NPs with uniform sizes of less than 5 nm. Their magnetic and optical properties were further evaluated, and they exhibited spin-glass-like behavior and unique ultra-violet absorbance, respectively. The developed SPMPs themselves preserve a scale-out feature with a current productivity of at least 13.0 g/(day-line) according to the Fe, Co or Ni content.

语种英语
WOS记录号WOS:000341287300065
引用统计
被引频次:18[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51738
专题北京大学第一临床医学院_放射治疗科
北京大学第一临床医学院_医学影像科
作者单位1.Beihang Univ, Sch Mat Sci & Engn, Beijing 100191, Peoples R China
2.Univ Sci & Technol Beijing, Sch Math & Phys, Beijing 100083, Peoples R China
3.Beijing Univ Chem Technol, Coll Mat Sci & Engn, State Key Lab Chem Resources Engn, Beijing 100029, Peoples R China
4.Peking Univ, Dept Radiol, Hosp 1, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Shen, Xiaomiao,Song, Yujun,Li, Shuai,et al. Spatiotemporal-resolved nanoparticle synthesis via simple programmed microfluidic processes[J]. RSC ADVANCES,2014,4(64):34179-34188.
APA Shen, Xiaomiao.,Song, Yujun.,Li, Shuai.,Li, Runsheng.,Ji, Shaoxia.,...&Wang, Xiaoying.(2014).Spatiotemporal-resolved nanoparticle synthesis via simple programmed microfluidic processes.RSC ADVANCES,4(64),34179-34188.
MLA Shen, Xiaomiao,et al."Spatiotemporal-resolved nanoparticle synthesis via simple programmed microfluidic processes".RSC ADVANCES 4.64(2014):34179-34188.
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