IR@PKUHSC  > 北京大学口腔医学院  > 儿童口腔科
学科主题口腔医学
Changes in Dental Plaque Microbial Richness and Oral Behavioral Habits during Caries Development in Young Chinese Children
Hao, Wenjing1; Xu, He1; Chen, Xiaochi2; Zhou, Qiong1; Zhang, Ping4; Chen, Feng3; Qin, Man1
关键词Children Denaturing Gradient Gel Electrophoresis Dental Plaque Longitudinal Study Microbial Richness
刊名CARIES RESEARCH
2015
DOI10.1159/000366505
49期:2页:116-123
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dentistry, Oral Surgery & Medicine
资助者Beijing Medical Research and Development ; Capital Clinical Characteristics Applied Research Projects ; Construct Program of the National Key Discipline ; Beijing Medical Research and Development ; Capital Clinical Characteristics Applied Research Projects ; Construct Program of the National Key Discipline
研究领域[WOS]Dentistry, Oral Surgery & Medicine
关键词[WOS]EARLY-CHILDHOOD CARIES ; PRESCHOOL-CHILDREN ; FEEDING PRACTICES ; BIRTH COHORT ; PCR-DGGE ; COMMUNITIES ; HEALTH ; DIET
英文摘要

Objective: To detect changes in the microbial richness of dental plaque and oral behaviors during caries development in young Chinese children. Methods: Supragingival plaque samples and a survey of oral behaviors of 130 children aged 3 at baseline were analyzed at 6 months and 12 months. Total DNA was isolated from all samples and PCR-denaturing gradient gel electrophoresis analysis was conducted. Results: In the follow-up, 44 children had caries or cavity fillings at 6 months, a further 28 children had caries or cavity fillings at 12 months. The other 58 children remained caries-free at 12 months. According to the changes in caries status at the 12-month follow-up, all participants were divided into three groups: caries-free, caries at 6 months and caries at 12 months. The changes in oral behaviors during the 12-month follow-up were not significantly different in the three groups. The frequency of eating sweets and eating sweets before sleeping was significantly different among the three groups at baseline. At baseline, the average detectable bands of caries in the 12-month caries group were similar to those of the caries-free group; both of them were higher than that of the 6-month caries group. At 6 months, the average detectable bands of the 12-month caries group were significantly lower than that of the caries-free group although the children of the 12-month caries group were caries-free at that time. Conclusions: For young Chinese children, the high frequency of eating sweets and eating sweets before sleeping are riskfactors of caries onset, and the decrease in microbial richness could occur 6 months before the onset of caries. (C) 2015 S. Karger AG, Basel

语种英语
所属项目编号2009-2032 ; Z121107001012028
资助者Beijing Medical Research and Development ; Capital Clinical Characteristics Applied Research Projects ; Construct Program of the National Key Discipline ; Beijing Medical Research and Development ; Capital Clinical Characteristics Applied Research Projects ; Construct Program of the National Key Discipline
WOS记录号WOS:000351117500004
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51760
Collection北京大学口腔医学院_儿童口腔科
作者单位1.Haidian Maternal & Child Hlth Hosp, Dept Dent, Beijing, Peoples R China
2.Peking Univ, Sch & Hosp Stomatol, Dept Pediat Dent, Beijing 100081, Peoples R China
3.Peking Univ, Sch & Hosp Stomatol, Dept Oral Microorganisms, Beijing 100081, Peoples R China
4.Peking Univ, Sch & Hosp Stomatol, Cent Lab, Beijing 100081, Peoples R China
Recommended Citation
GB/T 7714
Hao, Wenjing,Xu, He,Chen, Xiaochi,et al. Changes in Dental Plaque Microbial Richness and Oral Behavioral Habits during Caries Development in Young Chinese Children[J]. CARIES RESEARCH,2015,49(2):116-123.
APA Hao, Wenjing.,Xu, He.,Chen, Xiaochi.,Zhou, Qiong.,Zhang, Ping.,...&Qin, Man.(2015).Changes in Dental Plaque Microbial Richness and Oral Behavioral Habits during Caries Development in Young Chinese Children.CARIES RESEARCH,49(2),116-123.
MLA Hao, Wenjing,et al."Changes in Dental Plaque Microbial Richness and Oral Behavioral Habits during Caries Development in Young Chinese Children".CARIES RESEARCH 49.2(2015):116-123.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
谷歌学术
谷歌学术Similar articles in
[Hao, Wenjing]'s Articles
[Xu, He]'s Articles
[Chen, Xiaochi]'s Articles
百度学术
百度学术Similar articles in
[Hao, Wenjing]'s Articles
[Xu, He]'s Articles
[Chen, Xiaochi]'s Articles
必应学术
必应学术Similar articles in
[Hao, Wenjing]'s Articles
[Xu, He]'s Articles
[Chen, Xiaochi]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.