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学科主题: 临床医学
题名:
Perioperative Acute Myocardial Infarction Increases Mortality Following Noncardiac Surgery
作者: Li, Shuang-Ling; Wang, Dong-Xin; Wu, Xin-Min; Li, Nan; Xie, Ya-Qing
关键词: perioperative acute myocardial infarction ; mortality ; noncardiac surgery ; survival
刊名: JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
发表日期: 2013-12-01
DOI: 10.1053/j.jvca.2013.03.029
卷: 27, 期:6, 页:1277-1281
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Anesthesiology ; Cardiac & Cardiovascular Systems ; Respiratory System ; Peripheral Vascular Disease
研究领域[WOS]: Anesthesiology ; Cardiovascular System & Cardiology ; Respiratory System
关键词[WOS]: RISK
英文摘要:

Objective: To provide insight into diagnosis, treatment, and prevention of perioperative myocardial infarction (PMI).

Design: The authors retrospectively analyzed PMI characteristics in patients undergoing noncardiac surgery and identified risk factors for death.

Setting: An affiliated teaching hospital with about 1500 beds.

Participants: The authors screened electronic medical records and retrospectively analyzed clinical data from 117,856 patients who underwent noncardiac surgery during the period from August 2003 through June 2011.

Interventions: Patients were divided into two groups based on survival at 30 days after PMI.

Measurements and Main Results: PMI was reported in 61 patients, for an overall incidence rate of 5.2 per 10,000. PMI incidence increased significantly with age, with a rate of 0.97 per 10,000 for the 45- to 60-year-old group, and increasing to a rate of 40.4 per 10,000 for the >75-year-old group (p < 0.001). The mortality rate of non-PMI patients (n = 117,795) was 0.32%, whereas the mortality rate for the 61 PMI patients was 36.1% (p < 0.001). PM! occurred acutely (within 48 to 72 hours of surgery) in the majority of patients (78.7%), and only 18% of these patients complained of chest pain. The majority of patients who suffered PM! had non-ST segment elevation acute myocardial infarction (78.7%). By multiple logistic regression analysis, lack of anticoagulation/antiplatelet therapy and cardiogenic shock were independent risk factors for death in PMI patients (p = 0.001 for both).

Conclusions: PMI incidence increased significantly with advanced age. PMI increased mortality following noncardiac surgery. The independent risk factors for death in PMI patients following noncardiac surgery were lack of anticoagulation/antiplatelet therapy and cardiogenic shock. (C) 2013 Elsevier Inc. All rights reserved.

语种: 英语
WOS记录号: WOS:000328181700032
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51775
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: Peking Univ, Hosp 1, Dept Anesthesiol & Surg Intens Care, Beijing 100034, Peoples R China

Recommended Citation:
Li, Shuang-Ling,Wang, Dong-Xin,Wu, Xin-Min,et al. Perioperative Acute Myocardial Infarction Increases Mortality Following Noncardiac Surgery[J]. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA,2013,27(6):1277-1281.
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