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学科主题: 药学
题名:
Novel Bile Acids from Bear Bile Powder and Bile of Geese
作者: Bi, Dan; Chai, Xing-Yun; Song, Yue-Lin; Lei, Yu; Tu, Peng-Fei
关键词: Selenaretos thibetanus ; Anser anser domesticus ; bile acid
刊名: CHEMICAL & PHARMACEUTICAL BULLETIN
发表日期: 2009-05-01
卷: 57, 期:5, 页:528-531
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy ; Chemistry
关键词[WOS]: PRIMARY BILIARY-CIRRHOSIS ; URSODEOXYCHOLIC ACID ; IDENTIFICATION
英文摘要:

Two new bile acids, tauroselocholic acid (1) and tauroansocholic acid (2), a new natural bile acid, cygnocholic acid (3) were respectively isolated from bear bile powder Selenaretos thibetanus CUVIER and bile of geese Anser anser domesticus, together with seven known compounds. By spectrum analysis of MS, 1D and 2D NMR, the structures of the new compounds were elucidated as 3 alpha,7 alpha, 9 alpha-trihydroxy-5 beta-cholan-24-oic acid N-[2-sulfoethyl] amide (1), 3 alpha,5,7 alpha-trihydroxy-5 beta-cholan-24-oic acid N-[2-sulfoethyl] amide (2) and 3 alpha,7 alpha,15 alpha-trihydroxy-5 beta-cholan-24-oic acid (3).

语种: 英语
WOS记录号: WOS:000266046900019
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51922
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Bi, Dan,Chai, Xing-Yun,Song, Yue-Lin,et al. Novel Bile Acids from Bear Bile Powder and Bile of Geese[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2009,57(5):528-531.
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