北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 运动医学研究所  > 期刊论文
学科主题: 临床医学
题名:
Effect of repeated freezing-thawing on the Achilles tendon of rabbits
作者: Chen, Lianxu1; Wu, Yanping2; Yu, Jiakuo1; Jiao, Zhaode2; Ao, Yingfang1; Yu, Changlong1; Wang, Jianquan1; Cui, Guoqing1
关键词: Repeated freezing-thawing ; Achilles tendon ; Histology ; Biomechanics
刊名: KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
发表日期: 2011-06-01
DOI: 10.1007/s00167-010-1278-y
卷: 19, 期:6, 页:1028-1034
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Orthopedics ; Sport Sciences ; Surgery
研究领域[WOS]: Orthopedics ; Sport Sciences ; Surgery
关键词[WOS]: ANTERIOR CRUCIATE LIGAMENT ; ARTHROSCOPIC RECONSTRUCTION ; ENDOSCOPIC RECONSTRUCTION ; PATELLAR LIGAMENT ; ALLOGRAFT ; AUTOGRAFT ; RUPTURES ; GRAFTS ; KNEE
英文摘要:

The increased use of allograft tissue in the reconstruction of anterior cruciate ligament has brought more focus to the effect of storage and treatment on allograft. The purpose of this study was to observe the effect of histology and biomechanics on Achilles tendon in rabbits through repeated freezing-thawing before allograft tendon transplantation. Rabbit Achilles tendons were harvested and processed according to the manufacture′s protocol of tissue bank, and freezing-thawing was repeated three times (group 1) and ten times (group 2). Those received only one cycle were used as controls. Then, tendons in each group were selected randomly to make for histological observations and biomechanics test. Histological observation showed that the following changes happened as the number of freezing-thawing increased: the arrangement of tendon bundles and collagen fibrils became disordered until ruptured, cells disrupted and apparent gaps appeared between tendon bundle because the formation of ice crystals. There were significant differences between the experimental and control groups in the values of maximum load, energy of maximum load and maximum stress, whereas no significant differences existed in other values such as stiffness, maximum strain, elastic modulus, and energy density. Therefore, repeated freezing-thawing had histological and biomechanical effect on Achilles tendon in rabbits before allograft tendon transplantation. This indicates that cautions should be taken in the repeated freezing-thawing preparation of allograft tendons in clinical application.

语种: 英语
WOS记录号: WOS:000290727400029
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51949
Appears in Collections:北京大学第三临床医学院_运动医学研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Hosp 3, Inst Sports Med, Beijing 100191, Peoples R China
2.Weifang Yidu Cent Hosp, Dept Orthopaed Surg, Qingzhou 262500, Shandong, Peoples R China

Recommended Citation:
Chen, Lianxu,Wu, Yanping,Yu, Jiakuo,et al. Effect of repeated freezing-thawing on the Achilles tendon of rabbits[J]. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY,2011,19(6):1028-1034.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Chen, Lianxu]'s Articles
[Wu, Yanping]'s Articles
[Yu, Jiakuo]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Chen, Lianxu]‘s Articles
[Wu, Yanping]‘s Articles
[Yu, Jiakuo]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace