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Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China
Atkinson, J. Hampton1; Jin, Hua1; Shi, Chuan2; Yu, Xin2; Duarte, Nichole A.1; Casey, Corinna Young1; Franklin, Donald R., Jr.1; Vigil, Ofilio1; Cysique, Lucette1; Wolfson, Tanya1; Riggs, P. Katie1; Gupta, Saurabh1; Letendre, Scott1; Marcotte, Thomas D.1; Grant, Igor1; Wu, Zunyou3; Heaton, Robert K.1; HIV Neurobehav Res Ctr Grp1
关键词Hiv Aids Depression Suicide China
刊名JOURNAL OF AFFECTIVE DISORDERS
2011-05-01
DOI10.1016/j.jad.2010.10.039
130期:3页:421-428
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Psychiatry
研究领域[WOS]Neurosciences & Neurology ; Psychiatry
关键词[WOS]HIV HEALTH SURVEY ; QUALITY-OF-LIFE ; MEDICAL OUTCOMES ; UNITED-STATES ; HONG-KONG ; DISORDERS ; PREVALENCE ; DEPRESSION ; MEN ; HIV/AIDS
英文摘要

Background: China′s HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday function, employment, and life quality.

Methods: HIV-infected (HIV+) former plasma donors (N=203) and HIV-negative (HIV-) donor controls (N=198) completed the World Mental Health Survey Composite International Diagnostic Interview to determine lifetime major depressive disorder (MDD), substance use disorders, and suicidality. Current mood and suicidality were assessed with the Beck Depression Inventory-II. Everyday function was measured by an Activity of Daily Living questionnaire; life quality was evaluated by the Medical Outcomes Study - HIV.

Results: HIV+ participants had known their infected status for 2 years on average. Most were taking antiretroviral treatment and had frank AIDS. Rates of current MDD were similar across groups (1-2%), but HIV+ had a higher frequency of lifetime MDD (14% vs. 5%, p<.05). Its onset preceded date of known infection in one-third of cases. Alcoholism was the only substance use disorder detected; HIV+ had a higher proportion of lifetime substance use diagnoses (14% vs. 6%, p<.05). Depression and AIDS independently predicted worse daily functioning and life quality, and unemployment.

Limitations: The epicenter of China HIV has moved into urban injection drug users, limiting the representativeness of this sample.

Conclusions: High rates of MDD and its impact suggest that in China, as elsewhere, comprehensive care requires detection and treatment of mood disorder. Published by Elsevier B.V.

语种英语
WOS记录号WOS:000291192100008
项目编号R01 MH073433 ; MH 62515 ; MH 62512
资助机构National Institute of Mental Health (NIMH)
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51950
专题北京大学精神卫生研究所
北京大学精神卫生研究所_精神科
作者单位1.Univ Calif San Diego, HIV Neurobehav Res Ctr, San Diego, CA 92103 USA
2.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
3.China Ctr Dis Control, Beijing, Peoples R China
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GB/T 7714
Atkinson, J. Hampton,Jin, Hua,Shi, Chuan,et al. Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China[J]. JOURNAL OF AFFECTIVE DISORDERS,2011,130(3):421-428.
APA Atkinson, J. Hampton.,Jin, Hua.,Shi, Chuan.,Yu, Xin.,Duarte, Nichole A..,...&HIV Neurobehav Res Ctr Grp.(2011).Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China.JOURNAL OF AFFECTIVE DISORDERS,130(3),421-428.
MLA Atkinson, J. Hampton,et al."Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China".JOURNAL OF AFFECTIVE DISORDERS 130.3(2011):421-428.
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