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学科主题: 精神卫生
题名:
Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China
作者: Atkinson, J. Hampton1; Jin, Hua1; Shi, Chuan2; Yu, Xin2; Duarte, Nichole A.1; Casey, Corinna Young1; Franklin, Donald R., Jr.1; Vigil, Ofilio1; Cysique, Lucette1; Wolfson, Tanya1; Riggs, P. Katie1; Gupta, Saurabh1; Letendre, Scott1; Marcotte, Thomas D.1; Grant, Igor1; Wu, Zunyou3; Heaton, Robert K.1; HIV Neurobehav Res Ctr Grp1
关键词: HIV ; AIDS ; Depression ; Suicide ; China
刊名: JOURNAL OF AFFECTIVE DISORDERS
发表日期: 2011-05-01
DOI: 10.1016/j.jad.2010.10.039
卷: 130, 期:3, 页:421-428
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Psychiatry
研究领域[WOS]: Neurosciences & Neurology ; Psychiatry
关键词[WOS]: HIV HEALTH SURVEY ; QUALITY-OF-LIFE ; MEDICAL OUTCOMES ; UNITED-STATES ; HONG-KONG ; DISORDERS ; PREVALENCE ; DEPRESSION ; MEN ; HIV/AIDS
英文摘要:

Background: China′s HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday function, employment, and life quality.

Methods: HIV-infected (HIV+) former plasma donors (N=203) and HIV-negative (HIV-) donor controls (N=198) completed the World Mental Health Survey Composite International Diagnostic Interview to determine lifetime major depressive disorder (MDD), substance use disorders, and suicidality. Current mood and suicidality were assessed with the Beck Depression Inventory-II. Everyday function was measured by an Activity of Daily Living questionnaire; life quality was evaluated by the Medical Outcomes Study - HIV.

Results: HIV+ participants had known their infected status for 2 years on average. Most were taking antiretroviral treatment and had frank AIDS. Rates of current MDD were similar across groups (1-2%), but HIV+ had a higher frequency of lifetime MDD (14% vs. 5%, p<.05). Its onset preceded date of known infection in one-third of cases. Alcoholism was the only substance use disorder detected; HIV+ had a higher proportion of lifetime substance use diagnoses (14% vs. 6%, p<.05). Depression and AIDS independently predicted worse daily functioning and life quality, and unemployment.

Limitations: The epicenter of China HIV has moved into urban injection drug users, limiting the representativeness of this sample.

Conclusions: High rates of MDD and its impact suggest that in China, as elsewhere, comprehensive care requires detection and treatment of mood disorder. Published by Elsevier B.V.

语种: 英语
所属项目编号: R01 MH073433 ; MH 62515 ; MH 62512
项目资助者: National Institute of Mental Health (NIMH)
WOS记录号: WOS:000291192100008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/51950
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Univ Calif San Diego, HIV Neurobehav Res Ctr, San Diego, CA 92103 USA
2.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
3.China Ctr Dis Control, Beijing, Peoples R China

Recommended Citation:
Atkinson, J. Hampton,Jin, Hua,Shi, Chuan,et al. Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China[J]. JOURNAL OF AFFECTIVE DISORDERS,2011,130(3):421-428.
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