IR@PKUHSC  > 北京大学第一临床医学院  > 男科中心
学科主题临床医学
Recent advances in andrology-related stem cell research
Lin, Ching-Shwun1; Xin, Zhong-Cheng2; Deng, Chun-Hua3; Ning, Hongxiu1; Lin, Guiting1; Lue, Tom F.1
关键词Stem Cells Bone Marrow Stem Cells Adipose Tissue-derived Stem Cells Erectile Dysfunction Male Infertility
刊名ASIAN JOURNAL OF ANDROLOGY
2008-03-01
DOI10.1111/j.1745-7262.2008.00389.x
10期:2页:171-175
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Andrology ; Urology & Nephrology
研究领域[WOS]Endocrinology & Metabolism ; Urology & Nephrology
关键词[WOS]HUMAN ADIPOSE-TISSUE ; MESENCHYMAL STROMAL CELLS ; SMOOTH-MUSCLE-CELLS ; VERSUS-HOST-DISEASE ; GERM-CELLS ; PROGENITOR CELLS ; SALVAGE THERAPY ; IN-VITRO ; DIFFERENTIATION ; LIPOSUCTION
英文摘要

Stem cells hold great promise for regenerative medicine because of their ability to self-renew and to differentiate into various cell types. Although embryonic stem cells (BSC) have greater differentiation potential than adult stem cells, the former is lagging in reaching clinical applications because of ethical concerns and governmental restrictions. Bone marrow stem cells (BMSC) are the best- studied adult stem cells (ASC) and have the potential to treat a wide variety of diseases, including erectile dysfunction (ED) and male infertility. More recently discovered adipose tissue-derived stem cells (ADSC) are virtually identical to bone marrow stem cells in differentiation and therapeutic potential, but are easier and safer to obtain, can be harvested in larger quantities, and have the associated benefit of reducing obesity. Therefore, ADSC appear to be a better choice for future clinical applications. We have previously shown that ESC could restore the erectile function of neurogenic ED in rats, and we now have evidence that ADSC could do so as well. We are also investigating whether ADSC can differentiate into Leydig, Sertoli and male germ cells. The eventual goal is to use ADSC to treat male infertility and testosterone deficiency.

语种英语
WOS记录号WOS:000253604100001
引用统计
被引频次:37[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/51961
专题北京大学第一临床医学院_男科中心
作者单位1.Univ Calif San Francisco, Sch Med, Dept Urol, Knuppe Mol Urol Lab, San Francisco, CA 94143 USA
2.Peking Univ First Hosp, Androl Ctr, Beijing 100009, Peoples R China
3.Sun Yat Sen Univ, Affairs Hosp 1, Dept Urol, Guangzhou 510080, Peoples R China
推荐引用方式
GB/T 7714
Lin, Ching-Shwun,Xin, Zhong-Cheng,Deng, Chun-Hua,et al. Recent advances in andrology-related stem cell research[J]. ASIAN JOURNAL OF ANDROLOGY,2008,10(2):171-175.
APA Lin, Ching-Shwun,Xin, Zhong-Cheng,Deng, Chun-Hua,Ning, Hongxiu,Lin, Guiting,&Lue, Tom F..(2008).Recent advances in andrology-related stem cell research.ASIAN JOURNAL OF ANDROLOGY,10(2),171-175.
MLA Lin, Ching-Shwun,et al."Recent advances in andrology-related stem cell research".ASIAN JOURNAL OF ANDROLOGY 10.2(2008):171-175.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Lin, Ching-Shwun]的文章
[Xin, Zhong-Cheng]的文章
[Deng, Chun-Hua]的文章
百度学术
百度学术中相似的文章
[Lin, Ching-Shwun]的文章
[Xin, Zhong-Cheng]的文章
[Deng, Chun-Hua]的文章
必应学术
必应学术中相似的文章
[Lin, Ching-Shwun]的文章
[Xin, Zhong-Cheng]的文章
[Deng, Chun-Hua]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。