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学科主题临床医学
Identification problems with sterile fungi, illustrated by a keratitis due to a non-sporulating Chaetomium-like species
Mootha, V. Vinod2; Shahinpoor, P.3; Sutton, Deanna A.4; Xin, Lian1,9; Najafzadeh, M. J.5; De Hoog, G. Sybren1,6,7,8
关键词Fungal Keratitis Papulaspora Chaetomium
刊名MEDICAL MYCOLOGY
2012-05-01
DOI10.3109/13693786.2011.611179
50期:4页:361-367
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Mycology ; Veterinary Sciences
资助者Research to Prevent Blindness, Inc ; Research to Prevent Blindness, Inc
研究领域[WOS]Mycology ; Veterinary Sciences
关键词[WOS]PAPULASPORA ; ASPERGILLUS ; MYCOLOGY
英文摘要

A 39-year-old farm worker was injured in her right eye by a piece of wire, which resulted in a corneal ulcer unresponsive to antibiotic treatment. The clinical appearance was that of a corneal infiltrate with feathery borders resembling fungal keratitis. Corneal scrapings were collected and the patient was started on natamycin 5% eye drops, fluconazole 0.3% eye drops, and oral fluconazole. A non-sporulating fungus was isolated from the samples. Based upon macroscopic and microscopic morphologic features, it was provisionally identified as a Papulaspora species due to the fact that members of this genus generally do not form diagnostically useful conidia. However, it was found through the use of ITS sequencing that the isolate clustered within the ascomycete genus Chaetomium. The sequence did not fully match with any sequences of available ex-type strains of Chaetomium, Thielavia and Papulaspora and hence might belong to an undescribed specie. However, without diagnostic morphological features the taxon cannot be introduced as a novel member of the genus Chaetomium. Antifungal susceptibility testing was performed according to published standards. The corneal ulcer was successfully treated with six weeks of antifungal therapy.

语种英语
资助者Research to Prevent Blindness, Inc ; Research to Prevent Blindness, Inc
WOS记录号WOS:000302752900004
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52001
专题北京大学第一临床医学院_皮肤性病科
作者单位1.Mashhad Univ Med Sci, Fac Med, Dept Parasitol & Mycol, Mashhad, Iran
2.CBS KNAW Fungal Biodivers Ctr, NL-3508 AD Utrecht, Netherlands
3.Univ New Mexico, Hlth Sci Ctr, Albuquerque, NM 87131 USA
4.Univ Texas SW Med Ctr Dallas, Dallas, TX 75390 USA
5.Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA
6.Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, NL-1012 WX Amsterdam, Netherlands
7.Peking Univ, Hlth Sci Ctr, Res Ctr Med Mycol, Beijing 100871, Peoples R China
8.Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou 510275, Guangdong, Peoples R China
9.Huazhong Sci & Technol Univ, Tongji Med Coll, Union Hosp, Dept Dermatol & Venereol, Wuhan, Peoples R China
推荐引用方式
GB/T 7714
Mootha, V. Vinod,Shahinpoor, P.,Sutton, Deanna A.,et al. Identification problems with sterile fungi, illustrated by a keratitis due to a non-sporulating Chaetomium-like species[J]. MEDICAL MYCOLOGY,2012,50(4):361-367.
APA Mootha, V. Vinod,Shahinpoor, P.,Sutton, Deanna A.,Xin, Lian,Najafzadeh, M. J.,&De Hoog, G. Sybren.(2012).Identification problems with sterile fungi, illustrated by a keratitis due to a non-sporulating Chaetomium-like species.MEDICAL MYCOLOGY,50(4),361-367.
MLA Mootha, V. Vinod,et al."Identification problems with sterile fungi, illustrated by a keratitis due to a non-sporulating Chaetomium-like species".MEDICAL MYCOLOGY 50.4(2012):361-367.
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