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学科主题临床医学
Letrozole as primary therapy for endometrial hyperplasia in young women
Li, H. Z.; Chen, X. N.; Qiao, J.
关键词Aromatase Inhibitor Letrozole Endometrial Hyperplasia
刊名INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
2008
DOI10.1016/j.ijgo.2007.06.041
100期:1页:10-12
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Obstetrics & Gynecology
研究领域[WOS]Obstetrics & Gynecology
关键词[WOS]AROMATASE INHIBITOR ; POSTMENOPAUSAL WOMEN ; REPLACEMENT THERAPY ; BREAST-CANCER ; PHASE-I ; ESTROGEN ; EXPRESSION ; TISSUE
英文摘要

Objective: To study letrozole as a primary therapeutic agent for endometrial. hyperplasia with or without atypia in young women. Methods: Five premenopausal women presenting for infertility were diagnosed as having endometrial. hyperplasia. A second biopsy was performed after they were treated for 3 months with 2.5 mg of letrozole per day. Serum levels of estradiol and progesterone were measured each month. Results: Curettage of the endometrium at the end of treatment revealed no evidence of endometrial hyperptasia or atypia in any of the patients. Low serum levels of estradiol were found in all patients. Conclusion: This case series indicates that aromatase inhibitors deserve attention for the conservative treatment of endometrial. hyperplasia. However, more studies are needed to confirm the efficacy and safety of this agent. (c) 2007 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000253025900003
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52003
专题北京大学第三临床医学院_生殖医学中心
作者单位Peking Univ, Third Hosp, Ctr Reprod Med, Dept Obstet & Gynecol, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Li, H. Z.,Chen, X. N.,Qiao, J.. Letrozole as primary therapy for endometrial hyperplasia in young women[J]. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS,2008,100(1):10-12.
APA Li, H. Z.,Chen, X. N.,&Qiao, J..(2008).Letrozole as primary therapy for endometrial hyperplasia in young women.INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS,100(1),10-12.
MLA Li, H. Z.,et al."Letrozole as primary therapy for endometrial hyperplasia in young women".INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS 100.1(2008):10-12.
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