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学科主题: 临床医学
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The prevalence of Parkinson′s disease continues to rise after 80 years of age: a cross-sectional study of Chinese veterans
作者: Zou, Y. -M.1,2; Tan, J. -P.1; Li, N.3; Yang, J. -S.4; Yu, B. -C.5; Yu, J. -M.6; Du, W.7; Zhang, W. -J.8; Cui, L. -Q.9; Wang, Q. -S.10; Xia, X. -N.11; Li, J. -J.12; Zhou, P. -Y.13; Zhang, B. -H.14; Liu, Z. -Y.15; Zhang, S. -G.16; Sun, L. -Y.17; Liu, N.18; Deng, R. -X.19; Ma, L. -H.20; Chen, W. -J.21; Zhang, Y. -Q.22; Liu, J.1; Zhang, S. -M.1; Lan, X. -Y.1; Zhao, Y. -M.4; Wang, L. -N.3
关键词: Parkinson&prime ; s disease ; Prevalence ; Regional variation ; Chinese veterans ; oldest old
刊名: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
发表日期: 2014-12-01
卷: 18, 期:24, 页:3908-3915
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy
关键词[WOS]: TO-DOOR SURVEY ; POPULATION ; PD ; DISORDERS ; TAIWAN ; EUROPE ; CITY
英文摘要:

OBJECTIVE: The purpose of this study was to examine whether the prevalence of Parkinson′s disease (PD) continues to rise after 80 years of age.

METHODS: This is a two-stage, multi-center, cross-sectional study using a stratified cluster sampling approach was employed. Subjects included veterans at >= 60 years of age living in veterans′ communities for at least one month in 18 major cities across China. In the first step, possible PD was screened using a PD screening scale. Demographic and relevant information were collected. In the second step, PD diagnosis was established using the United Kingdom Parkinson′s Disease Society Brain Bank (UKPDSBB) diagnostic criteria.

RESULTS: The study was conducted during the period from December 2009 to December 2012. The study included 277 veterans′ communities. Among the approached 11,593 subjects, 9676 subjects, (9096 men, 580 women) responded. The response rate was 83.46%. The age was >= 80 years in 6722 (69.47%) subjects. A diagnosis of PD was established in 228 subjects (2.36%) in the entire sample. The rate of PD was 2.65% in those with an age of >= 80 years. The rate of PD increased with increasing age (0%, 1.84%, 2.60% and 3.68% in the subjects at < 70, 70-79, 80-89 and >= 90 years of age, respectively; chi(2) = 10.891, p = 0.001 in chi-square test). The rate of PD was higher in men (2.44%) than in women (1.46%) on the surface. However, no significant difference was detected (p = 0.241).

CONCLUSIONS: The prevalence of PD continues to increase beyond the age of 80 years. The prevalence of PD in Chinese veterans is not lower than that in other countries and regions.

语种: 英语
所属项目编号: 07BJZ04 ; 10BJZ19 ; 11BJZ09 ; 12BJZ46
项目资助者: Clinical Department of Geriatrics ; Geriatric Neurology Department of the PLA General Hospital ; Special Health Research Foundation of the Health Department of the PLA General Logistics Department
WOS记录号: WOS:000352210900027
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52038
Appears in Collections:北京大学第三临床医学院_临床流行病学研究中心_期刊论文

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作者单位: 1.Chinese PLA 401 Hosp, Dept Neurol, Qingdao, Peoples R China
2.Chinese PLA 451 Hosp, Dept Neurol, Xian, Peoples R China
3.Chinese PLA 252 Hosp, Cadre Dept, Biaoding, Peoples R China
4.Chinese PLA 253 Hosp, Dept Neurol, Hohhot, Peoples R China
5.Armed Police Forces, Gen Hosp, Cadre Dept, Beijing, Peoples R China
6.Nan Kai Univ, China Med Sch, Tianjin, Peoples R China
7.Chengdu Mil Command, Gen Hosp, Dept Neurol, Chengdu, Peoples R China
8.Lanzhou Mil Command, Gen Hosp, Dept Neurol, Lanzhou, Peoples R China
9.Chinese PLA 323 Hosp, Dept Neurol, Xian, Peoples R China
10.Bethune Int Peace Hosp, Dept Gerontol, Shijiazhuang, Peoples R China
11.Chinese PLA 107 Hosp, Dept Neurol, Yantai, Peoples R China
12.Chinese PLA 201 Hosp, Dept Neurol, Dalian, Peoples R China
13.Changhai Hosp, Dept Gerontol, Shanghai, Peoples R China
14.Navy Gen Hosp, Cadre Dept, Beijing, Peoples R China
15.Chinese PLA 264 Hosp, Dept Neurol, Taiyuan, Peoples R China
16.Chinese PLA 254 Hosp, Cadre Dept 3, Tianjin, Peoples R China
17.Chinese Peoples Liberat Army Gen Hosp, Dept Geriatr Neurol, Beijing 100853, Peoples R China
18.Peking Univ, Hosp 3, Res Ctr Clin Epidemiol, Beijing 100871, Peoples R China
19.Nanjing Mil Command, Fuzhou Gen Hosp, Cadre Dept 1, Fuzhou, Peoples R China
20.Guangzhou Mil Command, Gen Hosp, Cadre Dept 4, Guangzhou, Guangdong, Peoples R China
21.Chinese PLA 44 Hosp, Dept Internal Med 3, Guiyang, Guizhou, Peoples R China
22.Guangzhou Mil Command, Wuhan Gen Hosp, Dept Neurol, Wuhan, Peoples R China

Recommended Citation:
Zou, Y. -M.,Tan, J. -P.,Li, N.,et al. The prevalence of Parkinson&prime;s disease continues to rise after 80 years of age: a cross-sectional study of Chinese veterans[J]. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES,2014,18(24):3908-3915.
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