|Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China|
|Xiang, Yu-Tao1,2; Wang, Gang2; Guo, Tong2; Hu, Chen2; Ungvari, Gabor S.3,4; Kilbourne, Amy M.5,6; Lai, Kelly Y. C.1; Wong, Samuel Y. S.7; Si, Tian-Mei8,9; Zheng, Qi-Wen10; Chen, Da-Fang10; Fang, Yi-Ru11; Lu, Zheng12; Yang, Hai-Chen13; Hu, Jian14; Chen, Zhi-Yu15; Huang, Yi16; Sun, Jing17; Wang, Xiao-Ping18; Li, Hui-Chun19; Zhang, Jin-Bei20; Chiu, Helen F. K.1|
|收录类别||SCI ; SSCI|
|WOS标题词||Science & Technology|
|关键词[WOS]||INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW ; EPIDEMIOLOGIC SURVEY ; MOOD DISORDERS ; DSM-IV ; OUTPATIENTS ; LIFE ; EXPERIENCES ; PREVALENCE ; VALIDATION ; SYMPTOMS|
Purpose: Little is known about gender differences associated with major depressive disorder (MDD) in China. This study examined gender differences associated with other demographic and clinical characteristics and psychotropic drug treatment in Chinese patients with MDD.
Methods: A total of 1178 patients with MDD from 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide were enrolled. Cross-sectional data including patients′ demographic and clinical characteristics and prescriptions of psychotropic medications were recorded using a standardized protocol and data collection procedure.
Results: The sample consisted of 793 female and 385 male patients. Univariate analyses revealed that male patients were younger than female patients, had a younger age of onset of depression, had less lifetime depressive episodes and had more bipolar features (i.e. patients who screened positive for hypomanic symptoms on the 32-item Hypomania Checklist, but did not meet the diagnostic criteria for DSM-IV bipolar disorders as measured by the Mini International Neuropsychiatric Interview). Also, men were more likely to be employed than women and less likely to have depressive episodes following stressful life events. In multivariate analyses, being employed, having bipolar features and not having depressive episodes following stressful life events were independently associated with being a male patient with major depressive disorder. There was no difference in use of psychotropic medications by gender.
Conclusions: Most gender differences in MDD patients in this study are not consistent with findings of Western studies suggesting that gender differences in MDD may be determined by both biological and sociocultural differences among ethnically different patient populations. (C) 2013 Elsevier Inc. All rights reserved.
|资助机构||National Key Scientific and Technological Projects for the 11th Five-Year from the Ministry of Science and Technology of China ; AstraZeneca China|
|作者单位||1.Vet Adm Ann Arbor Ctr Clin Management Res, Ann Arbor, MI USA|
2.Minist Mental Hlth, Key Lab Mental Hlth, Beijing, Peoples R China
3.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
4.Hangzhou Seventh Peoples Hosp, Hangzhou, Zhejiang, Peoples R China
5.Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
6.Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China
7.Univ Notre Dame, Australia Marian Ctr, Perth, WA, Australia
8.Univ Western Australia, Sch Psychiat & Clin Neurosci, Perth, WA 6009, Australia
9.Univ Michigan, Sch Med, Dept Psychiat, Ann Arbor, MI USA
10.Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Hong Kong, Peoples R China
11.Peking Univ, Hlth Sci Ctr, Dept Epidemiol & Biostat, Beijing 100871, Peoples R China
12.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Div Mood Disorders, Shanghai 200030, Peoples R China
13.Tongji Univ, Sch Med, Shanghai Tongji Hosp, Shanghai 200092, Peoples R China
14.Shenzhen Mental Hlth Ctr, Div Mood Disorders, Shenzhen, Guangdong, Peoples R China
15.Harbin Med Univ, Hosp 1, Harbin, Heilongjiang Pr, Peoples R China
16.Sichuan Univ, West China Hosp, Chengdu, Sichuan Provinc, Peoples R China
17.Nanjing Med Univ, Affiliated Brain Hosp, Nanjing, Jiangsu, Peoples R China
18.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China
19.Zhejiang Univ, Coll Med, Affiliated Hosp 2, Hangzhou, Zhejiang, Peoples R China
20.Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou, Guangdong, Peoples R China
|Xiang, Yu-Tao,Wang, Gang,Guo, Tong,et al. Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China[J]. COMPREHENSIVE PSYCHIATRY,2013,54(8):1198-1202.|
|APA||Xiang, Yu-Tao.,Wang, Gang.,Guo, Tong.,Hu, Chen.,Ungvari, Gabor S..,...&Chiu, Helen F. K..(2013).Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China.COMPREHENSIVE PSYCHIATRY,54(8),1198-1202.|
|MLA||Xiang, Yu-Tao,et al."Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China".COMPREHENSIVE PSYCHIATRY 54.8(2013):1198-1202.|