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学科主题: 临床医学
题名:
En-face optical coherence tomography in the diagnosis and management of age-related macular degeneration and polypoidal choroidal vasculopathy
作者: Lau, Tiffany1; Wong, Ian Y.2; Iu, Lawrence2; Chhablani, Jay4; Yong, Tao5; Hideki, Koizumi6; Lee, Jacky3; Wong, Raymond1
关键词: Age-related macular degeneration ; en-face optical coherence tomography ; polypoidal choroidal vasculopathy
刊名: INDIAN JOURNAL OF OPHTHALMOLOGY
发表日期: 2015-05-01
DOI: 10.4103/0301-4738.159860
卷: 63, 期:5, 页:378-383
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: RETICULAR PSEUDODRUSEN ; GEOGRAPHIC ATROPHY ; OCT ; ANGIOGRAPHY ; FEATURES ; EYE
英文摘要:

Optical coherence tomography (OCT) is a noninvasive imaging modality providing high-resolution images of the central retina that has completely transformed the field of ophthalmology. While traditional OCT has produced longitudinal cross-sectional images, advancements in data processing have led to the development of en-face OCT, which produces transverse images of retinal and choroidal layers at any specified depth. This offers additional benefit on top of longitudinal cross-sections because it provides an extensive overview of pathological structures in a single image. The aim of this review was to discuss the utility of en-face OCT in the diagnosis and management of age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). En-face imaging of the inner segment/outer segment junction of retinal photoreceptors has been shown to be a useful indicator of visual acuity and a predictor of the extent of progression of geographic atrophy. En-face OCT has also enabled high-resolution analysis and quantification of pathological structures such as reticular pseudodrusen (RPD) and choroidal neovascularization, which have the potential to become useful markers for disease monitoring. En-face Doppler OCT enables subtle changes in the choroidal vasculature to be detected in eyes with RPD and AMD, which has significantly advanced our understanding of their pathogenesis. En-face Doppler OCT has also been shown to be useful for detecting the polypoid lesions and branching vascular networks diagnostic of PCV. It may therefore serve as a noninvasive alternative to fluorescein and indocyanine green angiography for the diagnosis of PCV and other forms of the exudative macular disease.

语种: 英语
WOS记录号: WOS:000357736600004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52069
Appears in Collections:北京大学第二临床医学院_眼科_期刊论文

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作者单位: 1.Hong Kong Eye Hosp, Dept Ophthalmol, Hong Kong, Hong Kong, Peoples R China
2.Univ Hong Kong, Dept Ophthalmol, Hong Kong, Hong Kong, Peoples R China
3.Caritas Med Ctr, Dept Ophthalmol, Hong Kong, Hong Kong, Peoples R China
4.LV Prasad Eye Inst, Dept Ophthalmol, Hyderabad, Telangana, India
5.Peking Univ, Peoples Hosp, Dept Ophthalmol, Beijing 100871, Peoples R China
6.Tokyo Womens Med Univ, Dept Ophthalmol, Tokyo, Japan

Recommended Citation:
Lau, Tiffany,Wong, Ian Y.,Iu, Lawrence,et al. En-face optical coherence tomography in the diagnosis and management of age-related macular degeneration and polypoidal choroidal vasculopathy[J]. INDIAN JOURNAL OF OPHTHALMOLOGY,2015,63(5):378-383.
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