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学科主题基础医学
Intraocular Pressure Fluctuation in Patients With Primary Open-angle Glaucoma Combined With High Myopia
Yang, Yingxin1,2; Li, Zhen2,4; Wang, Ningli2; Wu, Lie1; Zhen, Yi2; Wang, Tao2; Ren, Caixia5; Peng, Xiaoxia3; Hao, Jie2; Xia, Yanting6
关键词High-tension Primary Open-angle Glaucoma Intraocular Pressure Fluctuations High Myopia Exercise
刊名JOURNAL OF GLAUCOMA
2014
DOI10.1097/IJG.0b013e31825afc9d
23期:1页:19-22
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Ophthalmology
研究领域[WOS]Ophthalmology
关键词[WOS]VISUAL-FIELD PROGRESSION ; OCULAR HYPERTENSION ; RISK-FACTOR ; AEROBIC EXERCISE ; INTERVENTION ; ASSOCIATION ; MODERATE ; PATTERN ; TRIAL
英文摘要

Purpose:To investigate whether patients with primary open-angle glaucoma combined with high myopia (POAG-HM) have short-term intraocular pressure (IOP) fluctuations at resting conditions over 24 hours and after dynamic exercise.Methods:Prospective Control Clinical Study. Eighty eyes of 80 high-tension Chinese POAG patients only on prostaglandin analog locally were categorized as per their degree of myopia (myopes 6 D or more, n=30 and between -0.76 and -5.99 D, n=29) or without myopia (n=21). Twenty-four-hour IOP fluctuations at resting conditions were observed in protocol 1, and IOP fluctuations after 10-minute exercise at 20% maximum Watt (Wmax) and followed by 5 minutes of exercise at 60% Wmax were observed in protocol 2.Results:Twenty-four-hour IOP fluctuations at resting conditions were not statistically significant among groups (P=0.58). After 10 minutes of moderate (20% Wmax) exercise, patients with POAG-HM had significant IOP decrease (3.502.76 mm Hg) over other subjects (analysis of covariance, age, as a covariate, was controlled, P=0.02). After 5 minutes of heavy (60% Wmax) exercise, patients with POAG-HM had significantly a greater postexercise IOP decrease (7.57 +/- 3.47 mm Hg) than other groups (P=0.00).Conclusions:High-tension POAG patients with high myopia on only pharmacological glaucoma therapy have significantly greater IOP fluctuations after moderate and heavy exercise and do not have greater 24-hour IOP fluctuations at resting conditions.

语种英语
WOS记录号WOS:000329805200008
项目编号Z090507017709009
资助机构Beijing Municipal Science &amp ; Technology Commission
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52070
专题北京大学基础医学院
作者单位1.China Acad Chinese Med Sci, Guanganmen Hosp, Beijing, Peoples R China
2.Capital Med Univ, Beijing Tongren Hosp, Beijing Tongren Eye Ctr, Beijing 100730, Peoples R China
3.Capital Med Univ, Sch Publ Hlth & Family Med, Dept Epidemiol & Biostat, Beijing 100730, Peoples R China
4.Capital Med Univ, Xuan Wu Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
5.Peking Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Beijing 100871, Peoples R China
6.Beijing Univ Chinese Med, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Yang, Yingxin,Li, Zhen,Wang, Ningli,et al. Intraocular Pressure Fluctuation in Patients With Primary Open-angle Glaucoma Combined With High Myopia[J]. JOURNAL OF GLAUCOMA,2014,23(1):19-22.
APA Yang, Yingxin.,Li, Zhen.,Wang, Ningli.,Wu, Lie.,Zhen, Yi.,...&Xia, Yanting.(2014).Intraocular Pressure Fluctuation in Patients With Primary Open-angle Glaucoma Combined With High Myopia.JOURNAL OF GLAUCOMA,23(1),19-22.
MLA Yang, Yingxin,et al."Intraocular Pressure Fluctuation in Patients With Primary Open-angle Glaucoma Combined With High Myopia".JOURNAL OF GLAUCOMA 23.1(2014):19-22.
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