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学科主题: 精神卫生
题名:
Lower serum interleukin-2 levels in schizophrenic patients with tardive dyskinesia
作者: Liu, Haibo1; Kang, Yimin1; Liang, Jun2; Li, Cunbao1; Xiu, Meihong3; Chen, Dachun3; Yang, Fude3; Wang, Fang3; Wu, Guiying4; Haile, Colin N.4; Kosten, Therese A.4; Kosten, Thomas R.3,4; Zhang, Xiang Yang3,4
关键词: Schizophrenia ; Tardive dyskinesia ; Interleukin ; Immune
刊名: PSYCHIATRY RESEARCH
发表日期: 2012-07-30
DOI: 10.1016/j.psychres.2012.01.002
卷: 198, 期:2, 页:329-331
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Psychiatry
研究领域[WOS]: Psychiatry
关键词[WOS]: PSYCHOPATHOLOGY ; ANTIPSYCHOTICS
英文摘要:

We determined serum interleukin-2 (IL-2) levels between schizophrenic patients with (n = 45) and without tardive dyskinesia (TD; n = 45) compared to normal controls (n = 50). TD patients had lower serum IL-2 levels than non-TD patients, but higher IL-2 levels than normal controls. IL-2 was associated with the negative symptoms of schizophrenia, but not with TD severity. Immune disturbance may be involved in the pathophysiology of TD. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

语种: 英语
所属项目编号: 03T-459 ; 05T-726 ; K05-DA0454 ; P50-DA18827 ; U01-MH79639
项目资助者: Stanley Medical Research Institute ; Department of Veterans Affairs, VISN 16, Mental Illness Research, Education and Clinical Center (MIRECC), United States National Institutes of Health
WOS记录号: WOS:000311987000030
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52086
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Beijing HuiLongGuan Hosp, Ctr Biol Psychiat, Beijing, Peoples R China
2.Inner Mongolia Med Coll, Hohhot 010059, Peoples R China
3.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
4.Baylor Coll Med, Menninger Dept Psychiat & Behav Sci, Houston, TX 77030 USA

Recommended Citation:
Liu, Haibo,Kang, Yimin,Liang, Jun,et al. Lower serum interleukin-2 levels in schizophrenic patients with tardive dyskinesia[J]. PSYCHIATRY RESEARCH,2012,198(2):329-331.
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