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The prevalence of left ventricular hypertrophy in Chinese hemodialysis patients is higher than that in peritoneal dialysis patients
Tian, Jun-Ping1; Wang, Tao2; Wang, Hong3; Cheng, Li-Tao2; Tian, Xin-Kui2; Lindholm, Bengt1; Axelsson, Jonas1; Du, Feng-He1
关键词Peritoneal Dialysis Hemodialysis Left Ventricular Hypertrophy Volume Hemodynamics
刊名RENAL FAILURE
2008
DOI10.1080/08860220801964178
30期:4页:391-400
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]STAGE RENAL-DISEASE ; ARTERIOVENOUS-FISTULA CLOSURE ; LONG-TERM CAPD ; FOLLOW-UP ; TRANSPLANT RECIPIENTS ; SURVIVAL ; VOLUME ; HYPERTENSION ; ASSOCIATION ; THERAPY
英文摘要

Background. Left ventricular hypertrophy (LVH) is common in dialysis patients, and an independent predictor of mortality. While recent studies have shown no differences in mortality between the two most common dialysis modalities, hemodialysis (HD) and peritoneal dialysis (PD), their impact on LVH is controversial. We thus performed cardiac ultrasound studies in prevalent dialysis patients receiving either HD or PD and compared LVH. Methods. We included 48 HD and 62 PD patients receiving treatment for at least three months in our dialysis center. All patients underwent echocardiographic examination and blood pressure measurements immediately following therapy. Volume status was assessed by bioelectrical impedance analysis. Results. There was no baseline difference in demographics or comorbidities between HD and PD patients. As expected, extracellular water (ECW) in post-HD patients was significantly lower than that in pre-HD and PD patients, while cardiac output (CO) and systolic blood pressure (SBP) were higher in pre-HD than that in post-HD or PD patients. There was no significant difference in CO or SBP between post-HD and PD patients. Left ventricular mass index (LVMI) was markedly higher in HD patients as compared to PD patients. Thus, the prevalence of LVH according to the Framingham criteria was 68.8% in HD patients and 45.2% in PD patients. Subgroup analysis showed similar results in the patients who had been on single-modality dialysis for at least two years and in the anuric patients. Finally, in a linear regression model (r(2) = 0.364, p < 0.001), SBP, treatment modality (to be in HD), and ECW were all independent predictors of LVMI. Conclusions. In a cross-sectional analysis of prevalent Chinese patients, we found a higher LVMI and a higher prevalence of LVH in HD than in PD patients. As LVMI was associated with high blood pressure and volume overload, we suggest that in these patients, PD may preserve more physiological hemodynamics even during long-term therapy.

语种英语
WOS记录号WOS:000256352500008
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52109
专题北京大学第三临床医学院_肾内科
作者单位1.Shanxi Fenyang Hosp, Dept Internal Med, Taiyuan, Shanxi, Peoples R China
2.Capital Med Univ, Beijing Tiantan Hosp, Div Cardiol, Beijing 100050, Peoples R China
3.Peking Univ, Div Nephrol, Hosp 3, Beijing 100871, Peoples R China
4.Karolinska Inst, Div Baxter Novum, Dept Clin Sci Intervent & Technol, Stockholm, Sweden
5.Karolinska Inst, Div Renal Med, Dept Clin Sci Intervent & Technol, Stockholm, Sweden
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GB/T 7714
Tian, Jun-Ping,Wang, Tao,Wang, Hong,et al. The prevalence of left ventricular hypertrophy in Chinese hemodialysis patients is higher than that in peritoneal dialysis patients[J]. RENAL FAILURE,2008,30(4):391-400.
APA Tian, Jun-Ping.,Wang, Tao.,Wang, Hong.,Cheng, Li-Tao.,Tian, Xin-Kui.,...&Du, Feng-He.(2008).The prevalence of left ventricular hypertrophy in Chinese hemodialysis patients is higher than that in peritoneal dialysis patients.RENAL FAILURE,30(4),391-400.
MLA Tian, Jun-Ping,et al."The prevalence of left ventricular hypertrophy in Chinese hemodialysis patients is higher than that in peritoneal dialysis patients".RENAL FAILURE 30.4(2008):391-400.
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