IR@PKUHSC  > 北京大学深圳医院  > 皮肤性病科
学科主题临床医学
Chronic urticaria in Chinese population: a hospital-based multicenter epidemiological study
Zhong, H.1; Song, Z.1; Chen, W.2; Li, H.3; He, L.4; Gao, T.5; Fang, H.6; Guo, Z.7; Xv, J.8; Yu, B.9; Gao, X.10; Xie, H.11; Gu, H.12,13; Luo, D.14; Chen, X.15; Lei, T.16; Gu, J.17; Cheng, B.18; Duan, Y.19; Xv, A.20; Zhu, X.21; Hao, F.1
关键词Epidemiology Urticaria
刊名ALLERGY
2014-03-01
DOI10.1111/all.12338
69期:3页:359-364
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Allergy ; Immunology
资助者National Science Found of China ; Clinical Research Found of Third Military Medical University ; National Science Found of China ; Clinical Research Found of Third Military Medical University
研究领域[WOS]Allergy ; Immunology
关键词[WOS]FOOD ALLERGY ; CLASSIFICATION ; PREVALENCE ; GUIDELINE
英文摘要

BackgroundThe epidemiologic profiles of chronic urticaria (CU) vary considerably among regions, and few such data are available from China.

MethodsWe performed a multicenter open questionnaire investigation about the clinical and laboratory features of CU, defined as recurrent wheals with/without angioedema lasting for 6weeks, among 3027 patients.

ResultsFemale preponderance was observed (female/male ratio, 1.46:1). The mean age at diagnosis was 34.713.8years, and the mean disease duration was 18.5 +/- 46.1months (range, 1.5-127months). Patients were classified as having chronic spontaneous urticaria (CSU, 61.0% of patients), physical urticaria (PU, 26.2%), or other urticaria types (OU, 2.3%). Nocturnal attacks were reported by 60% of cases. The Urticaria Activity Score (UAS) in patients with CSU was 3.8 +/- 1.4. The mean Dermatology Life Quality Index was 7.3 +/- 3.4 (range 0-30). Induction or exacerbation of wheals with alcohol drinking was reported by 55.7% of patients. Chronic hepatitis B was less prevalent in our CU patients compared with the general Chinese population (2.7% vs 7%). Positive autologous serum skin tests (ASSTs) were observed in 66.9% of patients. Patients with positive ASST had higher UAS, greater angioedema frequencies, longer disease durations, and poorer QoL compared with patients with negative ASST (P<0.05).

ConclusionIn this Chinese population, CU usually affected youth, and CSU was the most common subtype. Autoreactivity and alcohol consumption were the top two triggers for CU, whereas latent infectious and chronic inflammatory diseases were not as common as in previous reports.

语种英语
所属项目编号81271754 ; 81072447 ; 2010XLC11
资助者National Science Found of China ; Clinical Research Found of Third Military Medical University ; National Science Found of China ; Clinical Research Found of Third Military Medical University
WOS记录号WOS:000331358400009
Citation statistics
Cited Times:12[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52128
Collection北京大学深圳医院_皮肤性病科
作者单位1.Jiangsu Prov Hosp, Dept Dermatol, Nanjing, Jiangsu, Peoples R China
2.Sichuan Prov Peoples Hosp, Dept Dermatol, Chengdu, Peoples R China
3.Shenyang 7 Peoples Hosp, Dept Dermatol, Shenyang, Peoples R China
4.Third Mil Med Univ, Southwest Hosp, Dept Dermatol, Chongqing 400038, Peoples R China
5.Tech Univ Munich, Dept Dermatol & Allergy, D-80290 Munich, Germany
6.Chongqing Med Univ, Affiliated Hosp 1, Dept Dermatol, Chongqing, Peoples R China
7.Kunming Med Coll, Hosp 1, Dept Dermatol, Kunming, Peoples R China
8.Fourth Mil Med Univ, Xijing Hosp, Dept Dermatol, Xian 710032, Peoples R China
9.Zhejiang Univ, Sch Med, Affiliated Hosp 1, Dept Dermatol, Hangzhou 310003, Zhejiang, Peoples R China
10.Sichuan Univ, West China Hosp, Dept Dermatol, Chengdu 610064, Peoples R China
11.Fudan Univ, Huashan Hosp, Dept Dermatol, Shanghai 200433, Peoples R China
12.Peking Univ, Shenzhen Hosp, Dept Dermatol, Shenzhen, Peoples R China
13.China Med Univ, Affiliated Hosp 1, Dept Dermatol, Shenyang, Peoples R China
14.Cent S Univ, Xiangya Hosp, Dept Dermatol, Changsha, Hunan, Peoples R China
15.Chinese Acad Med Sci, Inst Dermatol, Nanjing, Jiangsu, Peoples R China
16.Peking Union Med Coll, Nanjing, Jiangsu, Peoples R China
17.Second Mil Med Univ, Changhai Hosp, Dept Dermatol, Shanghai, Peoples R China
18.Fujian Med Univ, Affiliated Hosp 1, Dept Dermatol, Fuzhou, Peoples R China
19.Wuhan Integrated TCM & Western Med Hosp, Dept Dermatol, Wuhan, Peoples R China
20.Hangzhou Third Peoples Hosp, Dept Dermatol, Hangzhou, Zhejiang, Peoples R China
21.Peking Univ, Hosp 1, Dept Dermatol, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Zhong, H.,Song, Z.,Chen, W.,et al. Chronic urticaria in Chinese population: a hospital-based multicenter epidemiological study[J]. ALLERGY,2014,69(3):359-364.
APA Zhong, H..,Song, Z..,Chen, W..,Li, H..,He, L..,...&Hao, F..(2014).Chronic urticaria in Chinese population: a hospital-based multicenter epidemiological study.ALLERGY,69(3),359-364.
MLA Zhong, H.,et al."Chronic urticaria in Chinese population: a hospital-based multicenter epidemiological study".ALLERGY 69.3(2014):359-364.
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