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学科主题: 药学
题名:
Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species
作者: Li, Rui; Xiang, Cheng; Ye, Min; Li, Hui-Fang; Zhang, Xing; Guo, De-An
关键词: Curcuminoids ; Curcuma spp. ; Herbal medicines ; HPLC-UV-MS
刊名: FOOD CHEMISTRY
发表日期: 2011-06-15
DOI: 10.1016/j.foodchem.2010.12.014
卷: 126, 期:4, 页:1890-1895
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
研究领域[WOS]: Chemistry ; Food Science & Technology ; Nutrition & Dietetics
关键词[WOS]: TANDEM MASS-SPECTROMETRY ; ELECTROSPRAY-IONIZATION ; HPLC METHOD ; ANGIOGENESIS ; BISDEMETHOXYCURCUMIN ; DEMETHOXYCURCUMIN ; CHROMATOGRAPHY ; PROLIFERATION ; ANTIOXIDANT ; SUPPRESSION
英文摘要:

A validated and sensitive HPLC-UV-MS method was developed for qualitative and quantitative analysis of curcuminoids in eight herbal medicines derived from four Curcuma species. The samples were separated on a YMC ODS-A C(18) column with a gradient elution of acetonitrile and 0.1% formic acid. Curcumin, demethoxycurcumin and bisdemethoxycurcumin showed good linearity (r > 0.9998) in the concentration ranges of 4.88-625, 4.29-550 and 3.98-510 mu g/mL, respectively. The results suggested that the contents of three major curcuminoids in different herbal medicines varied significantly. Curcuminoids were only detected in Jianghuang, HuangsiYujin, and PengEzhu. Amongst them, Jianghuang contained the highest amounts of curcuminoids (40.36 mg/g), which were almost 20 times higher than HuangsiYujin (1.94 mg/g) and 400 times higher than PengEzhu (0.098 mg/g). Furthermore, amongst the Jianghuang samples collected from different areas, samples from Sichuan Province contained remarkably higher amounts of curcuminoids (22.21-40.36 mg/g) than other cultivation regions. (c) 2010 Elsevier Ltd. All rights reserved.

语种: 英语
所属项目编号: 985-2-119-121
项目资助者: Peking University
WOS记录号: WOS:000287952000054
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52162
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Li, Rui,Xiang, Cheng,Ye, Min,et al. Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species[J]. FOOD CHEMISTRY,2011,126(4):1890-1895.
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