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Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species
Li, Rui; Xiang, Cheng; Ye, Min; Li, Hui-Fang; Zhang, Xing; Guo, De-An
关键词Curcuminoids Curcuma Spp. Herbal Medicines Hplc-uv-ms
刊名FOOD CHEMISTRY
2011-06-15
DOI10.1016/j.foodchem.2010.12.014
126期:4页:1890-1895
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
研究领域[WOS]Chemistry ; Food Science & Technology ; Nutrition & Dietetics
关键词[WOS]TANDEM MASS-SPECTROMETRY ; ELECTROSPRAY-IONIZATION ; HPLC METHOD ; ANGIOGENESIS ; BISDEMETHOXYCURCUMIN ; DEMETHOXYCURCUMIN ; CHROMATOGRAPHY ; PROLIFERATION ; ANTIOXIDANT ; SUPPRESSION
英文摘要

A validated and sensitive HPLC-UV-MS method was developed for qualitative and quantitative analysis of curcuminoids in eight herbal medicines derived from four Curcuma species. The samples were separated on a YMC ODS-A C(18) column with a gradient elution of acetonitrile and 0.1% formic acid. Curcumin, demethoxycurcumin and bisdemethoxycurcumin showed good linearity (r > 0.9998) in the concentration ranges of 4.88-625, 4.29-550 and 3.98-510 mu g/mL, respectively. The results suggested that the contents of three major curcuminoids in different herbal medicines varied significantly. Curcuminoids were only detected in Jianghuang, HuangsiYujin, and PengEzhu. Amongst them, Jianghuang contained the highest amounts of curcuminoids (40.36 mg/g), which were almost 20 times higher than HuangsiYujin (1.94 mg/g) and 400 times higher than PengEzhu (0.098 mg/g). Furthermore, amongst the Jianghuang samples collected from different areas, samples from Sichuan Province contained remarkably higher amounts of curcuminoids (22.21-40.36 mg/g) than other cultivation regions. (c) 2010 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000287952000054
项目编号985-2-119-121
资助机构Peking University
引用统计
被引频次:32[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52162
专题北京大学药学院
北京大学药学院_天然药物学系
北京大学第一临床医学院_手术室
作者单位Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Li, Rui,Xiang, Cheng,Ye, Min,et al. Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species[J]. FOOD CHEMISTRY,2011,126(4):1890-1895.
APA Li, Rui,Xiang, Cheng,Ye, Min,Li, Hui-Fang,Zhang, Xing,&Guo, De-An.(2011).Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species.FOOD CHEMISTRY,126(4),1890-1895.
MLA Li, Rui,et al."Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species".FOOD CHEMISTRY 126.4(2011):1890-1895.
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