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学科主题: 公共卫生
题名:
Temporal trends of main reproductive characteristics in ten urban and rural regions of China: the China Kadoorie Biobank study of 300 000 women
作者: Lewington, Sarah1,2; Li, LiMing3,4; Murugasen, Serini1,2; Hong, Lai-san1,2; Yang, Ling1,2; Guo, Yu4; Bian, Zheng4; Collins, Rory1,2; Chen, Junshi5; He, Hui6; Wu, Ming7; He, Tianyou8; Ren, Xiaolan9; Meng, Jinhuai10; Peto, Richard1,2; Chen, Zhengming1,2; China Kadoorie Biobank Study1
关键词: Reproductive ; temporal trends ; China ; cohort study
刊名: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
发表日期: 2014-08-01
DOI: 10.1093/ije/dyu035
卷: 43, 期:4, 页:1252-1262
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Public, Environmental & Occupational Health
研究领域[WOS]: Public, Environmental & Occupational Health
关键词[WOS]: 1944-1945 DUTCH FAMINE ; TERM-FOLLOW-UP ; BREAST-CANCER ; RISK-FACTORS ; AGE ; MENARCHE ; MENOPAUSE ; POPULATION ; FERTILITY ; EXPOSURE
英文摘要:

Background: Chinese women′s reproductive patterns have changed significantly over the past several decades. However, relatively little is known about the pace and characteristics of these changes either overall or by region and socioeconomic status.

Methods: We examined the cross-sectional data from the China Kadoorie Biobank cohort study that recruited 300 000 women born between 1930 and 1974 (mean age: 51 years) from 10 socially diverse urban and rural regions of China. Temporal trends in several self-reported reproductive characteristics, and effect modification of these trends by area and education (as a surrogate for socioeconomic status), were examined.

Results: The overall mean age at menarche was 15.4 (standard deviation 1.9) years, but decreased steadily over the 45 birth cohorts from 16.1 to 14.3 years, except for an anomalous increase of similar to 1 year for women exposed to the 1958-61 famine in early adolescence. Similarly large changes were seen for other characteristics: mean parity fell (urban: 4.9 to 1.1; rural: 5.9 to 1.4); mean age at first birth increased (urban: 19.0 to 25.9 years; rural: 18.3 to 23.8 years); and birth spacing increased after 1980 to over 5 years. Breastfeeding declined after 1950 in urban and, after 1980, in rural women; and 68% of urban and 48% of rural women experienced a terminated pregnancy. Mean age at menopause increased from 47.9 to 49.3 years.

Conclusions There have been striking changes in reproductive factors over time and between areas among these Chinese women. Their effects on major chronic diseases should be investigated.

语种: 英语
所属项目编号: 088158/Z/09/Z ; 2011BAI09B01
项目资助者: Kadoorie Charitable Foundation in Hong Kong ; Wellcome Trust in the UK ; Chinese Ministry of Science and Technology ; UK Medical Research Council ; British Heart Foundation (BHF) ; Cancer Research UK
WOS记录号: WOS:000343935200033
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52165
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Univ Oxford, Clin Trial Serv Unit, Oxford OX3 7LF, England
2.Univ Oxford, Epidemiol Studies Unit, Oxford OX3 7LF, England
3.Chinese Natl Ctr Food Safety Risk Assessment, Beijing, Peoples R China
4.Nangang Ctr Dis Control, Haerbin, Heilongjiang, Peoples R China
5.Jiangsu Ctr Dis Control, Nanjing, Jiangsu, Peoples R China
6.Huixian Ctr Dis Control, Huixian, Hennan, Peoples R China
7.Gansu Ctr Dis Control, Lanzhou, Gansu, Peoples R China
8.Liuzhou Ctr Dis Control, Liuzhou, Guangxi, Peoples R China
9.Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Beijing 100871, Peoples R China
10.Chinese Acad Med Sci, Beijing 100730, Peoples R China

Recommended Citation:
Lewington, Sarah,Li, LiMing,Murugasen, Serini,et al. Temporal trends of main reproductive characteristics in ten urban and rural regions of China: the China Kadoorie Biobank study of 300 000 women[J]. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY,2014,43(4):1252-1262.
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