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学科主题口腔医学
Ameloblastic fibroma: A review of published studies with special reference to its nature and biological behavior
Chen, Yan1; Wang, Jing-Ming1; Li, Tie-Jun1
关键词Ametoblastic Fibroma Odontogenic Tumor Jaws Behavior
刊名ORAL ONCOLOGY
2007-11-01
DOI10.1016/j.oraloncology.2007.05.009
43期:10页:960-969
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Oncology ; Dentistry, Oral Surgery & Medicine
研究领域[WOS]Oncology ; Dentistry, Oral Surgery & Medicine
关键词[WOS]MIXED ODONTOGENIC-TUMORS ; OF-THE-LITERATURE ; MALIGNANT-TRANSFORMATION ; FIBROSARCOMA ; JAWS ; SARCOMA ; INTERRELATIONSHIP ; MANAGEMENT ; ODONTOMAS ; INFANT
英文摘要

To further elucidate confusions with respect to the nature and biological behavior of ameloblastic fibroma (AF), available English-language literature since its first description in 1891 was reviewed. A total number of 123 cases with well-documented follow-up data were retrieved to evaluate various clinical, pathological and behavioral aspects of this tumor. AF tends to occur in the first two decades (89/123; 72.4%), but patients older than 22 years are not uncommon (30 cases). An overall recurrence rate of 33.3% (41 cases) is identified in reported cases who were treated by conservative (91.5%) and radical (8.5%) methods. Malignant transformation is evident in 14 recurrent tumors with an overall transformation rate of 11.4%. These data support the view that majority of AFs are true neoplasms. However, a small. number of AFs occurring in childhood may represent the primitive stage of a developing odontoma, as three of the reported recurrent AFs do show further maturation with formation of dental hard tissues. A significantly longer recurrence-free survival was noted in patients treated by radical. procedures in comparison to those treated by conservative methods and the age of patients at the first presentation was significantly related to malignant transformation of AF. As we are unable, at present, to differentiate a hamartomatous lesion from a neoplasm among this group of lesions merely on histologic grounds, age of the patients should be an important consideration when choosing therapeutic methods. Radical. surgery should not be employed for the treatment of AFs in young people. (C) 2007 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000250740300003
Citation statistics
Cited Times:24[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52170
Collection北京大学口腔医学院_口腔病理科
作者单位1.Liwan Dist Oral Hosp, Guangzhou, Guangdong, Peoples R China
2.Peking Univ, Sch Hosp Stomatol, Dept Oral Pathol, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Chen, Yan,Wang, Jing-Ming,Li, Tie-Jun. Ameloblastic fibroma: A review of published studies with special reference to its nature and biological behavior[J]. ORAL ONCOLOGY,2007,43(10):960-969.
APA Chen, Yan,Wang, Jing-Ming,&Li, Tie-Jun.(2007).Ameloblastic fibroma: A review of published studies with special reference to its nature and biological behavior.ORAL ONCOLOGY,43(10),960-969.
MLA Chen, Yan,et al."Ameloblastic fibroma: A review of published studies with special reference to its nature and biological behavior".ORAL ONCOLOGY 43.10(2007):960-969.
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