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Mixed adenocarcinoma, sarcomatoid carcinoma and adenosquamous carcinoma of the prostate: A case report
Zhang, Zhongfu1; Wang, Yadong2; Zhao, Qing2; Li, Ganhong2; Zhao, Xingqi2; Li, Jun2; Li, Xianxin3
关键词Adenocarcinoma Sarcomatoid Carcinoma Adenosquamous Carcinoma Prostate Carcinoma P53
刊名ONCOLOGY LETTERS
2014-11-01
DOI10.3892/ol.2014.2493
8期:5页:2325-2327
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology
研究领域[WOS]Oncology
关键词[WOS]CLINICAL-SIGNIFICANCE ; P53 ; CANCER
英文摘要

Adenosquamous carcinoma (ASC) and sarcomatoid carcinoma (SC) of the prostate are rare, but highly aggressive tumors. The occurrence of mixed carcinomas in the prostate is even more rarely reported. The present study reports the case of a 62-year-old male who was diagnosed with prostatic adenocarcinoma accompanied by multiple bone metastases, as shown by a needle biopsy and skeletal computed tomography scan. The patient was treated with hormonal therapy, but thereafter, specimens from a transurethral resection of the prostate (TURF) were found to be composed of three histologically distinct elements: ASC, SC and adenocarcinoma. The level of p53 was evaluated by immunohistochemistry in detail, and it was found that this was significantly increased in the TURF samples compared with the needle biopsy samples. The abnormal level of p53 was likely associated with the prognosis of the patient; the patient succumbed to prostate carcinoma two months after the confirmation of the diagnosis.

语种英语
WOS记录号WOS:000344424300080
项目编号200901015
资助机构Shenzhen Key Project of Science and Technology
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52178
专题北京大学深圳医院_泌尿外科
作者单位1.Shenzhen Univ, Dept Urol Surg, Shenzhen Peoples Hosp 2, Affiliated Hosp 1, Shenzhen 518036, Guangdong, Peoples R China
2.Fifth Affiliated Hosp, Dept Urol, Zunyi Med Coll, Zhuhai 519100, Guangdong, Peoples R China
3.Peking Univ, Dept Urol, Shenzhen Hosp, Shenzhen 518036, Guangdong, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Zhongfu,Wang, Yadong,Zhao, Qing,et al. Mixed adenocarcinoma, sarcomatoid carcinoma and adenosquamous carcinoma of the prostate: A case report[J]. ONCOLOGY LETTERS,2014,8(5):2325-2327.
APA Zhang, Zhongfu.,Wang, Yadong.,Zhao, Qing.,Li, Ganhong.,Zhao, Xingqi.,...&Li, Xianxin.(2014).Mixed adenocarcinoma, sarcomatoid carcinoma and adenosquamous carcinoma of the prostate: A case report.ONCOLOGY LETTERS,8(5),2325-2327.
MLA Zhang, Zhongfu,et al."Mixed adenocarcinoma, sarcomatoid carcinoma and adenosquamous carcinoma of the prostate: A case report".ONCOLOGY LETTERS 8.5(2014):2325-2327.
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