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学科主题: 临床医学
题名:
Mixed adenocarcinoma, sarcomatoid carcinoma and adenosquamous carcinoma of the prostate: A case report
作者: Zhang, Zhongfu1; Wang, Yadong2; Zhao, Qing2; Li, Ganhong2; Zhao, Xingqi2; Li, Jun2; Li, Xianxin3
关键词: adenocarcinoma ; sarcomatoid carcinoma ; adenosquamous carcinoma ; prostate carcinoma ; p53
刊名: ONCOLOGY LETTERS
发表日期: 2014-11-01
DOI: 10.3892/ol.2014.2493
卷: 8, 期:5, 页:2325-2327
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology
研究领域[WOS]: Oncology
关键词[WOS]: CLINICAL-SIGNIFICANCE ; P53 ; CANCER
英文摘要:

Adenosquamous carcinoma (ASC) and sarcomatoid carcinoma (SC) of the prostate are rare, but highly aggressive tumors. The occurrence of mixed carcinomas in the prostate is even more rarely reported. The present study reports the case of a 62-year-old male who was diagnosed with prostatic adenocarcinoma accompanied by multiple bone metastases, as shown by a needle biopsy and skeletal computed tomography scan. The patient was treated with hormonal therapy, but thereafter, specimens from a transurethral resection of the prostate (TURF) were found to be composed of three histologically distinct elements: ASC, SC and adenocarcinoma. The level of p53 was evaluated by immunohistochemistry in detail, and it was found that this was significantly increased in the TURF samples compared with the needle biopsy samples. The abnormal level of p53 was likely associated with the prognosis of the patient; the patient succumbed to prostate carcinoma two months after the confirmation of the diagnosis.

语种: 英语
所属项目编号: 200901015
项目资助者: Shenzhen Key Project of Science and Technology
WOS记录号: WOS:000344424300080
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52178
Appears in Collections:北京大学深圳医院_泌尿外科_期刊论文

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作者单位: 1.Shenzhen Univ, Dept Urol Surg, Shenzhen Peoples Hosp 2, Affiliated Hosp 1, Shenzhen 518036, Guangdong, Peoples R China
2.Fifth Affiliated Hosp, Dept Urol, Zunyi Med Coll, Zhuhai 519100, Guangdong, Peoples R China
3.Peking Univ, Dept Urol, Shenzhen Hosp, Shenzhen 518036, Guangdong, Peoples R China

Recommended Citation:
Zhang, Zhongfu,Wang, Yadong,Zhao, Qing,et al. Mixed adenocarcinoma, sarcomatoid carcinoma and adenosquamous carcinoma of the prostate: A case report[J]. ONCOLOGY LETTERS,2014,8(5):2325-2327.
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