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学科主题: 药学
题名:
Antioxidants and a new dihydroisocoumarins from Polygala hongkongensis Hemsl
作者: Wu, Jian-Feng1; Chen, Si-Bao1; Gao, Jing-Chun1; Song, Hao-Liang1; Wu, Li-Jun1; Chen, Shi-Lin1; Tu, Peng-Fei1
关键词: Polygala hongkongensis ; dihydroisocoumarins ; hongkongenin ; flavonoids ; antioxidant activities
刊名: NATURAL PRODUCT RESEARCH
发表日期: 2007
DOI: 10.1080/14786410701369391
卷: 21, 期:7, 页:580-584
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Applied ; Chemistry, Medicinal
研究领域[WOS]: Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: GLYCOSIDES ; FLAVONOIDS ; ESTERS ; ROOTS
英文摘要:

A new dihydroisocoumarins, 6-methoxy-8-hydroxy-3-(4-hydroxyphenyl) isochroman-1-one, named as hongkongenin (1), and seven known flavonoids were isolated from the methanol extract whole plant of Polygala hongkongensis Hemsl. Their structures were established on the basis of UV, IR, NMR, and MS spectral data. It is the first report of the occurrence of isocoumarins in Polygala, and the known compounds 2-8 were isolated from this plant for the first time. Flavonoids showed potent antioxidant activities in vitro against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, hydroxyl radicals, and reductive activity to Fe3+.

语种: 英语
WOS记录号: WOS:000247934300002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52182
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Foshan Univ, Foshan 528000, Peoples R China
2.Shenyang Pharmaceut Univ, Shenyang 110016, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
4.Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Shenzhen 518057, Peoples R China
5.Peking Union Med Coll, Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100094, Peoples R China

Recommended Citation:
Wu, Jian-Feng,Chen, Si-Bao,Gao, Jing-Chun,et al. Antioxidants and a new dihydroisocoumarins from Polygala hongkongensis Hemsl[J]. NATURAL PRODUCT RESEARCH,2007,21(7):580-584.
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