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IR@PKUHSC  > 北京大学第三临床医学院  > 肿瘤放疗科  > 期刊论文
学科主题: 临床医学
题名:
An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer
作者: Zhao, Nan; Yang, Ruijie; Wang, Junjie; Zhang, Xile; Li, Jinna
刊名: BIOMED RESEARCH INTERNATIONAL
发表日期: 2015
DOI: 10.1155/2015/613060
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
研究领域[WOS]: Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]: MODULATED RADIATION-THERAPY ; ARC THERAPY ; HELICAL TOMOTHERAPY ; PLAN QUALITY ; IMRT ; VMAT ; RADIOTHERAPY ; OPTIMIZATION ; DELIVERY ; VOLUME
英文摘要:

The study is to investigate a Hybrid IMRT/VMAT technique which combines intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) for the treatment of nonsmall cell lung cancer (NSCLC). Two partial arcs VMAT, 5-field IMRT, and hybrid plans were created for 15 patients with NSCLC. The hybrid plans were combination of 2 partial arcs VMAT and 5-field IMRT. The dose distribution of planning target volume (PTV) and organs at risk (OARs) for hybrid technique was compared with IMRT and VMAT. The monitor units (MUs) and treatment delivery time were also evaluated. Hybrid technique significantly improved the target conformity and homogeneity compared with IMRT and VMAT. The mean delivery time of IMRT, VMAT, and hybrid plans was 280 s, 114 s, and 327 s, respectively. The mean MUs needed for IMRT, VMAT, and hybrid plans were 933, 512, and 737, respectively. Hybrid technique reduced V-5, V-10, V-30, and MLD of normal lung compared with VMAT and spared the OARs better with fewer MUs with the cost of a little higher V-5, V-10, and mean lung dose (MLD) of normal lung compared with IMRT. Hybrid IMRT/VMAT can be a viable radiotherapy technique with better plan quality.

语种: 英语
所属项目编号: 81071237
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000363594600001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52188
Appears in Collections:北京大学第三临床医学院_肿瘤放疗科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Radiat Oncol, Beijing 100191, Peoples R China

Recommended Citation:
Zhao, Nan,Yang, Ruijie,Wang, Junjie,et al. An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer[J]. BIOMED RESEARCH INTERNATIONAL,2015.
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