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学科主题临床医学
An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer
Zhao, Nan; Yang, Ruijie; Wang, Junjie; Zhang, Xile; Li, Jinna
刊名BIOMED RESEARCH INTERNATIONAL
2015
DOI10.1155/2015/613060
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
研究领域[WOS]Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]MODULATED RADIATION-THERAPY ; ARC THERAPY ; HELICAL TOMOTHERAPY ; PLAN QUALITY ; IMRT ; VMAT ; RADIOTHERAPY ; OPTIMIZATION ; DELIVERY ; VOLUME
英文摘要

The study is to investigate a Hybrid IMRT/VMAT technique which combines intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) for the treatment of nonsmall cell lung cancer (NSCLC). Two partial arcs VMAT, 5-field IMRT, and hybrid plans were created for 15 patients with NSCLC. The hybrid plans were combination of 2 partial arcs VMAT and 5-field IMRT. The dose distribution of planning target volume (PTV) and organs at risk (OARs) for hybrid technique was compared with IMRT and VMAT. The monitor units (MUs) and treatment delivery time were also evaluated. Hybrid technique significantly improved the target conformity and homogeneity compared with IMRT and VMAT. The mean delivery time of IMRT, VMAT, and hybrid plans was 280 s, 114 s, and 327 s, respectively. The mean MUs needed for IMRT, VMAT, and hybrid plans were 933, 512, and 737, respectively. Hybrid technique reduced V-5, V-10, V-30, and MLD of normal lung compared with VMAT and spared the OARs better with fewer MUs with the cost of a little higher V-5, V-10, and mean lung dose (MLD) of normal lung compared with IMRT. Hybrid IMRT/VMAT can be a viable radiotherapy technique with better plan quality.

语种英语
WOS记录号WOS:000363594600001
项目编号81071237
资助机构National Natural Science Foundation of China
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52188
专题北京大学第三临床医学院_肿瘤放疗科
北京大学第二临床医学院_党委院长办公室
作者单位Peking Univ, Hosp 3, Dept Radiat Oncol, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Nan,Yang, Ruijie,Wang, Junjie,et al. An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer[J]. BIOMED RESEARCH INTERNATIONAL,2015.
APA Zhao, Nan,Yang, Ruijie,Wang, Junjie,Zhang, Xile,&Li, Jinna.(2015).An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer.BIOMED RESEARCH INTERNATIONAL.
MLA Zhao, Nan,et al."An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer".BIOMED RESEARCH INTERNATIONAL (2015).
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