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THE PREVALENCE OF HEMOPHILIA IN MAINLAND CHINA: A SYSTEMATIC REVIEW AND META-ANALYSIS
Qu, Yanji1; Nie, Xiaolu1; Yang, Zhirong1; Yin, Huan1; Pang, Yuanjie1; Dong, Peng2; Zhan, Siyan1
关键词Hemophilia Prevalence Registration Systematic Review Meta-analysis
刊名SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH
2014-03-01
45期:2页:455-466
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Public, Environmental & Occupational Health ; Infectious Diseases ; Tropical Medicine
研究领域[WOS]Public, Environmental & Occupational Health ; Infectious Diseases ; Tropical Medicine
英文摘要

The prevalence of hemophilia in mainland China was unclear; therefore, we can conducted a meta-analysis using existing data to evaluate the prevalence of hemophilia and its subtypes hemophilia A (HA), hemophilia B (HB), hemophilia C (HC) and Von Willebrand disease (VWD) in mainland China. We conducted a systematic literature review during August, 2011 using PubMed, EMBASE, and Cochrane Library in English and CBMDISK, CNKI, VIP and Wanfang Database in Chinese. We also carried out a search of general and specific hemophilia related websites. Reference lists of key reviews were hand-searched for further relevant research. Studies providing data of the prevalence of hemophilia or its subtypes were included. Meta-analysis was done using the generic inverse variance model. Twenty-two studies were included in the meta-analysis. The overall weighted prevalence of hemophilia was 3.6 per 100,000 and the prevalence among males was 5.5 per 100,000. The prevalence based on community studies was 2.9 per 100,000. The proportions of HA, HB, HC and VWD were 70.97%,16.13%,6.45% and 2.90%, respectively. The prevalences calculated in our study were higher than any previous studies in mainland China, but lower than the world-wide prevalences. The registration rate of hemophiliacs was extremely low. HA and HB were the major subtypes of hemophilia.

语种英语
WOS记录号WOS:000334729000025
资助机构Pfizer China
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52202
专题北京大学公共卫生学院
作者单位1.Phizer China, Beijing, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China
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GB/T 7714
Qu, Yanji,Nie, Xiaolu,Yang, Zhirong,et al. THE PREVALENCE OF HEMOPHILIA IN MAINLAND CHINA: A SYSTEMATIC REVIEW AND META-ANALYSIS[J]. SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH,2014,45(2):455-466.
APA Qu, Yanji.,Nie, Xiaolu.,Yang, Zhirong.,Yin, Huan.,Pang, Yuanjie.,...&Zhan, Siyan.(2014).THE PREVALENCE OF HEMOPHILIA IN MAINLAND CHINA: A SYSTEMATIC REVIEW AND META-ANALYSIS.SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH,45(2),455-466.
MLA Qu, Yanji,et al."THE PREVALENCE OF HEMOPHILIA IN MAINLAND CHINA: A SYSTEMATIC REVIEW AND META-ANALYSIS".SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH 45.2(2014):455-466.
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